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Mesylates

Known as: Methanesulfonates, Mesylate, Mesilates 
Organic salts or esters of methanesulfonic acid.
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Highly Cited
2006
Highly Cited
2006
Imatinib mesylate (Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous… 
Highly Cited
2005
Highly Cited
2005
Recent breakthroughs regarding gastrointestinal stromal tumors (GIST) and their pathogenesis have redefined diagnostic criteria… 
Highly Cited
2004
Highly Cited
2004
Imatinib mesylate, an inhibitor of the Bcr-Abl tyrosine kinase, has modest activity in refractory/relapsed Philadelphia… 
Highly Cited
2004
Highly Cited
2004
Idiopathic pulmonary fibrosis is a progressive and fatal fibrotic disease of the lungs with unclear etiology. Prior efforts to… 
Highly Cited
2003
Highly Cited
2003
The BCR/ABL tyrosine kinase inhibitor imatinib mesylate (Gleevec, STI571; Novartis, Basel, Switzerland) has shown remarkable… 
Highly Cited
2003
Highly Cited
2003
PURPOSE Most gastrointestinal stromal tumors (GISTs) express constitutively activated mutant isoforms of KIT or kinase platelet… 
Highly Cited
2002
Highly Cited
2002
BACKGROUND Constitutive activation of KIT receptor tyrosine kinase is critical in the pathogenesis of gastrointestinal stromal… 
Highly Cited
2002
Highly Cited
2002
BACKGROUND Chronic myelogenous leukemia (CML) is caused by the BCR-ABL tyrosine kinase, the product of the Philadelphia… 
Review
2002
Review
2002
This review discusses the development and uses of imatinib mesylate, a protein tyrosine kinase inhibitor useful in the treatment…