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Merimepodib

Known as: Carbamic acid, ((3-((((3-methoxy-4-(5-oxazolyl)phenyl)amino)carbonyl)amino)phenyl)methyl)-, (3S)-tetrahydro-3-furanyl ester, MMPD 
An inosine monophosphate dehydrogenase (IMPDH) inhibitor with activity against hepatitis C virus (HCV). IMPDH catalyzes the rate-limiting step in the… 
National Institutes of Health

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VX 497

Papers overview

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2018
2018
Preclinical Evaluation of the First Adenosine A1 Receptor Partial Agonist Radioligand for Positron Emission Tomography Imaging.
Central adenosine A1 receptor (A1R) is implicated in pain, sleep, substance use disorders, and neurodegenerative diseases, and is… 
2017
2017
MEANDERING OF MAIN PANCREATIC DUCT AS A CAUSE OF IDIOPATHIC RECURRENT ACUTE PANCREATITIS - A CASE REPORT
Meandering main pancreatic duct is an uncommon anatomical variation of main pancreatic duct characterized by abnormal curvature… 
2014
2014
Avaliação da cobertura do solo em sistemas de produção de milho e soja em Sergipe utilizando imagens aéreas.
O sistema de monocultivo empregado nas regioes produtoras de milho no Estado de Sergipe, associado ao preparo do solo com grades… 
2008
2008
Ultrasonic sensing and time-frequency analysis for detecting plastic deformation in an aluminum plate
We investigate the use of low frequency (10-70 MHz) laser ultrasound for the detection of fatigue damage. While high frequency… 
2007
2007
Time-Frequency based Classification of Structural Damage
The detection and classification of damage in complex materials and structures is essential from both safety and economic… 
2007
2007
Phase 2 study of the combination of merimepodib with peginterferon-alpha2b, and ribavirin in nonresponders to previous therapy for chronic hepatitis C.
2005
2005
A randomized, double-blind, placebo-controlled dose-escalation trial of merimepodib (VX-497) and interferon-alpha in previously untreated patients with chronic hepatitis C.
Inhibition of inosine monophosphate dehydrogenase (IMPDH) is one of several proposed mechanisms of action for ribavirin (RBV), a… 
2004
2004
Matrilysin‐1 (MMP‐7) and MMP‐19 are expressed by Paget's cells in extramammary Paget's disease
Background:  Extramammary Paget's disease (EMPD) is a rare malignant neoplasm of apocrine gland bearing skin characterized by… 
2003
2003
Analysis of surface electromyogram during gait by modified matching pursuit decomposition
The matching pursuit decomposition (MPD) with a redundant Gabor dictionary (GMPD) is a popular method to identify the time… 
1985
1985
Analysis of magnetic proportional drive circuits for bipolar junction transistors
A comparison is presented of some advantages and disadvantages of three popular magnetic proportional drive circuits for bipolar… 
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