Megakaryocyte Progenitor Cells

Known as: Cell, Megakaryocyte Progenitor, Progenitor, Megakaryocyte, Progenitor Cell, Megakaryocyte 
The parent cells that give rise to cells in the MEGAKARYOCYTE lineage, and ultimately BLOOD PLATELETS.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Infections are associated with extensive platelet consumption, representing a high risk for health. However, the mechanism… (More)
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Highly Cited
2013
Highly Cited
2013
Platelets have a key role in atherogenesis and its complications. Both hypercholesterolemia and increased platelet production… (More)
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Highly Cited
2009
Highly Cited
2009
GATA-2 is an essential transcription factor that regulates multiple aspects of hematopoiesis. Dysregulation of GATA-2 is a… (More)
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Highly Cited
2007
Highly Cited
2007
In the adult, platelets are derived from unipotential megakaryocyte colony-forming cells (Meg-CFCs) that arise from bipotential… (More)
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2006
2006
A major determinant in platelet production is the megakaryocyte (MK) size that is regulated both by ploidization and the increase… (More)
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Highly Cited
2004
Highly Cited
2004
The molecular pathways involved in the differentiation of hematopoietic progenitors are unknown. Here we report that chemokine… (More)
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Highly Cited
2002
Highly Cited
2002
Fibrinogen binding to integrin alphaIIbbeta3 mediates platelet aggregation and requires agonist-induced "inside-out" signals that… (More)
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Highly Cited
1998
Highly Cited
1998
CXCR4 is the receptor for the alpha-chemokine stromal cell-derived factor 1 (SDF-1) and has been shown to be expressed on a… (More)
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Highly Cited
1995
Highly Cited
1995
An in vitro culture system demonstrating the transitions from megakaryocyte progenitors to functional platelets is described… (More)
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1982
1982
An assay describing conditions for the maturation of single immature megakaryocytes in vitro is reported. Enriched populations of… (More)
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