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Matrix Attachment Regions

Known as: SAR Element, Matrix Attached Regions, Matrix-Attached Region 
Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or… 
National Institutes of Health

Related topics

Related topics

3 relations
Chromosomesaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2003
Highly Cited
2003
Thec-myc Insulator Element and Matrix Attachment Regions Definethe c-myc ChromosomalDomain
ABSTRACT Insulator elements and matrix attachment regions are essential for the organization of genetic information within the… 
Highly Cited
2000
Highly Cited
2000
Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.
The olfactory receptor (OR) gene cluster on human chromosome 17p13.3 was subjected to mixed shotgun automated DNA sequencing. The… 
Highly Cited
1998
Highly Cited
1998
Scaffold Attachment Region-Mediated Enhancement of Retroviral Vector Expression in Primary T Cells
ABSTRACT We have studied retroviral transgene expression in primary human lymphocytes. Our data demonstrate that transgene… 
Highly Cited
1996
Highly Cited
1996
A role for nuclear NF–κB in B–cell–specific demethylation of the Igκ locus
The immunoglobulin κ gene is specifically demethylated during B–cell maturation in a process which utilizes discrete cis–acting… 
Review
1996
Review
1996
Scaffold/matrix-attached regions: topological switches with multiple regulatory functions.
The nuclear matrix or scaffold that can be prepared and investigated in vitro has an affinity for distinct topological forms of… 
Highly Cited
1996
Highly Cited
1996
A matrix attachment region (MAR)-binding activity due to a p114 kilodalton protein is found only in human breast carcinomas and not in normal and benign breast disease tissues.
A M(r) 114,000 protein (p114) that specifically binds to nuclear matrix attachment DNA (matrix attachment region, MAR) from a… 
Review
1995
Review
1995
Scaffold/matrix-attached regions: structural properties creating transcriptionally active loci.
Highly Cited
1992
Highly Cited
1992
Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus
Picornaviral mRNAs have been shown to possess special structures in their 5' nontranslated regions (5'NTRs) that provide sites… 
Highly Cited
1991
Highly Cited
1991
DNA binding properties of the nuclear matrix and individual nuclear matrix proteins. Evidence for salt-resistant DNA binding sites.
Highly Cited
1990
Highly Cited
1990
Studies of an 800-kilobase DNA stretch of the Drosophila X chromosome: comapping of a subclass of scaffold-attached regions with sequences able to replicate autonomously in Saccharomyces cerevisiae
We have previously mapped scaffold-attached regions (SARs) on an 800-kilobase DNA walk from the Drosophila X chromosome. We have… 
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