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Mannich Bases

Known as: Bases, Mannich, Mannich Bases [Chemical/Ingredient], Mannich base 
Ketonic amines prepared from the condensation of a ketone with formaldehyde and ammonia or a primary or secondary amine. A Mannich base can act as… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Amines
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Narrower (3)

NC 1153NC 1175NC 758

Papers overview

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2016
2016
Synthesis of Fluorescent 2-Substituted 6-(Het)aryl-7-deazapurine Bases {4-(Het)aryl-pyrrolo[2,3-d]pyrimidines} by Aqueous Suzuki–Miyaura Cross-Coupling Reactions
Abstract A series of 4-(het)aryl-pyrrolo[2,3-d]pyrimidines [6-(het)aryl-7-deazapurine bases] bearing a H, NH2, CH3, F, or Cl… 
2011
2011
Synthesis and antimicrobial activity of some new Mannich base derivatives
A series of new mannich base derivatives 4-(furan-2-yl(2-(furan-2-yl methylene)hydrazinyl)methyl)morpholine(1-6) were synthesized… 
2011
2011
Mannich Synthesis of 2-(Thiazol-4-yl)-1h-benzimidazole-2-methylene Piperazinyl (2,5 -Diamino-1,3,4-thiadiazolyl) Oxamide and Evaluation of the Filaricidal Activity
2 Abstract: The search for new biologically active agents via Mannich synthesis has continued to generate interest. And as there… 
2003
2003
ANTIBACTERIAL ACTIVITES OF SOME NEW AMINO ACID-SCHI BASES
ABSTRACT Some new (N-indolidene-DL-glycine, N-indolidene-DL-alanine and N-indolidene-DL-valine) amino acid-Schiff bases were… 
2002
2002
Synthesis, Antibacterial And Antifungal Activities Of N-Mannich Bases Of 3-(N2- Pyrimethaminylimino) Isatin
Schiff base of isatin with pyrimethamine and its N-Mannich bases were synthesized. Their chemical structures have been confirmed… 
1990
1990
Evaluation of the citotoxicity of some Mannich base of acetophenone againt the EMT6 tumour
Highly Cited
1984
Highly Cited
1984
Synthesis and antibacterial activity of some 5-nitro-3-phenyliminoindol-2(3H)-ones and their N-Mannich bases.
The antimicrobial and antifungal activities of a series of 5-nitro-3-phenyliminoindol-2(3H)-ones and their 1-piperidinomethyl… 
1978
1978
Diuretic activity of Mannich base derivatives of ethacrynic acid and certain ethacrynic acid analogues.
Various Mannich base derivatives of selected phenoxyacetic acid type diuretics were synthesized and their diuretic potency was… 
1975
1975
Elevation of intracellular calcium ion concentration provokes production of 1,2-diacylglycerol and phosphatidate in human erythrocytes.
(AE,,,, of 0.08 m-cytochrome c, reduced with NaBH,, in 75m-sodium phosphate buffer, pH 7.5); the bulk of the activity was… 
1973
1973
Anticonvulsant properties of Mannich base derivatives of 2-phenylsuccinimide. 3.
Abstract Several Mannich base derivatives of 2‐phenylsuccinimide were synthesized and screened for anticonvulsant activity. All… 
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