Malignant neoplasm of adrenal cortex

Known as: Adrenal Cortex Cancer, Cancers, Adrenal Cortex, Malignant Tumor of Adrenal Cortex 
A primary (adrenal cortex carcinoma) or a metastatic malignant neoplasm affecting the adrenal cortex. (NCI05)
National Institutes of Health

Related topics

Related topics

13 relations
Abdominal CavityAdrenal Cortical AdenomaAdrenal GlandsAdrenal Medulla
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Broader (2)

Adrenal CortexTumors of Adrenal Cortex

Papers overview

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2014
2014
Analysis of circulating microRNAs in adrenocortical tumors
Differential diagnosis of adrenocortical adenoma (ACA) and carcinoma is of pivotal clinical relevance, as the prognosis and… (More)
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2013
2013
Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement.
CONTEXT Mitotane [1-(2-chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane] is the first-line treatment for metastatic… (More)
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Review
2009
Review
2009
Management of adrenal incidentaloma.
Clinically inapparent adrenal masses, or adrenal incidentalomas, are discovered inadvertently in the course of work-up or… (More)
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2007
2007
Somatic TP53 mutations are relatively rare among adrenocortical cancers with the frequent 17p13 loss of heterozygosity.
PURPOSE Allelic losses [loss of heterozygosity (LOH)] at the 17p13 locus are frequent (85%) in adrenocortical cancers. The tumor… (More)
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Highly Cited
2007
Highly Cited
2007
Adjuvant mitotane treatment for adrenocortical carcinoma.
BACKGROUND Adrenocortical carcinoma is a rare neoplasm characterized by a high risk of recurrence after radical resection… (More)
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Review
2005
Review
2005
Evaluation and treatment of Cushing's syndrome.
Cushing's syndrome results from sustained pathologic hypercortisolism caused by excessive corticotropin (ACTH) secretion by… (More)
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Highly Cited
2002
Highly Cited
2002
Results of laparoscopic adrenalectomy for suspected and unsuspected malignant adrenal neoplasms.
BACKGROUND Laparoscopic resection for malignant adrenal tumors is controversial, because they are rare and limited data exist in… (More)
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Highly Cited
2000
Highly Cited
2000
Streptozocin and o,p'DDD in the treatment of adrenocortical cancer patients: long-term survival in its adjuvant use.
BACKGROUND To evaluate the efficacy of streptozocin and o.p'DDD (SO) in adrenocortical cancer (ACC) patients since other… (More)
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Highly Cited
1994
Highly Cited
1994
p53 mutations in human adrenocortical neoplasms: immunohistochemical and molecular studies.
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at… (More)
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1992
1992
Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells.
The antitrypanosomal and antifiliarial drug suramin is currently under investigation for treatment of advanced malignancies… (More)
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