Macrocyclic Compounds

Known as: Compounds, Macrocyclic, Compounds, Macrocycle, Macrocycle Compounds 
Cyclic compounds with a ring size of approximately 1-4 dozen atoms.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2017
024619682017

Papers overview

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2017
2017
The design and synthesis of head-to-tail linked artificial macrocycles using the Ugi-reaction has been developed. This synthetic… (More)
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2017
2017
Macrocyclic compounds are central to the development of new drugs, but preparing them can be challenging because of the energy… (More)
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Review
2016
Review
2016
The macrocycles representing a unique chemical structure bridging conventional small molecules and large biomolecules, have… (More)
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2015
2015
A novel series of macrocyclic compounds were designed and synthesized as multi-target inhibitors targeting HDAC, FLT3 and JAK2… (More)
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2015
2015
Macrocyclic compounds occupy an important chemical space between small molecules and biologics and are prevalent in many natural… (More)
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2011
2011
BACKGROUND Useful probes of the intracellular environment that target a specific organelle in order to allow direct observation… (More)
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2009
2009
New linear and cyclic guanidines were synthesized and tested in vitro for their antifungal activity toward clinically relevant… (More)
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1996
1996
A family of macrocyclic compounds are described, together with their precursors. These cycles are composed of icosahedral… (More)
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1968
1968
For some years, work in this laboratory has been directed toward elucidation of the mechanism of selectivity of high-potassium… (More)
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