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MacAB-TolC complex

Known as: MacAB-TolC complex location, macrolide transporter MacAB-TolC complex, macrolide transporter MacAB-TolC complex location 
The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to… 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Membrane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
S‐Nitrosated alpha‐1‐acid glycoprotein exhibits antibacterial activity against multidrug‐resistant bacteria strains and synergistically enhances the effect of antibiotics
Alpha‐1‐acid glycoprotein (AGP) is a major acute‐phase protein. Biosynthesis of AGP increases markedly during inflammation and… 
2017
2017
Expression of TolC and Organic Solvent Tolerance of Escherichia Coli Ciprofloxacin Resistant Mutants
AcrAB-TolC is a major efflux pump in Escherichia coli. It was reported that tolC is overexpressed and involves in improving the… 
2015
2015
ANTICANCER DRUGS AS POTENTIAL INHIBITORS OF ACRAB-TOLC OF MULTIDRUG RESISTANT ESCHERICHIA COLI: AN IN SILICO MOLECULAR MODELING AND DOCKING STUDY
Objective: Overexpression of AcrAB-TolC protein complex is often associated with the virulence of multidrug-resistant bacteria… 
2013
2013
Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Escherichia coli.
Resistance to ciprofloxacin in Escherichia coli is increasing parallel to increased use of fluoroquinolones both in The… 
2013
2013
Treatment of Escherichia coli BW 25113 with Subinhibitory Levels of Kanamycin Results in Antibiotic Cross-Resistance and TolC Upregulation
To determine whether the efflux pump and outer membrane protein system, AcrAB-TolC, in Escherichia coli could be upregulated for… 
2011
2011
A reporter platform for the monitoring of in vivo conformational changes in AcrB.
AcrB is an inner membrane protein in Escherichia coli that is a component of a triplex AcrA-AcrB-TolC (AcrAB-TolC) multidrug… 
2011
2011
Elastic network model‐based normal mode analysis reveals the conformational couplings in the tripartite AcrAB‐TolC multidrug efflux complex
The AcrAB‐TolC drug efflux system, energized by proton movement down the transmembrane electrochemical gradient, is responsible… 
2009
2009
The role of intra- and extragenic compensatory mutations in the suppression of fluoroquinolone resistance in a Salmonella Typhimurium gyrA mutant (D87G).
OBJECTIVES The live vaccine strain TAD Salmonella vacT (vacT) carrying gyrA mutations W59R, G75A, D87G and A866S shows resistance… 
2008
2008
Role of global regulator Rma for multidrug efflux-mediated fluoroquinolone resistance in Salmonella.
The genetic basis for multidrug resistance (mdr) due to overexpression of mdr efflux pumps in Escherichia coli usually includes… 
2005
2005
High hydrostatic pressure treatment impairs AcrAB-TolC pump resulting in differential loss of deoxycholate tolerance in Escherichia coli.
We reported previously that high hydrostatic pressure-injured stationary phase cells of Escherichia coli K-12 lost their… 
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