MVT 101

Known as: L-Argininamide, N-(2-((N-(N-acetyl-L-threonyl)-L-isoleucyl)amino)hexyl)-L-norleucyl-L-glutaminyl-, (S)-, MVT-101 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2007
0119922007

Papers overview

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2007
2007
The human immunodeficiency virus 1 (HIV-1) protease (PR) is an aspartyl protease essential for HIV-1 viral infectivity. HIV-1 PR… (More)
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2004
2004
The structure of a crystal complex of the chemically synthesized protease of human immunodeficiency virus 1 with a heptapeptide… (More)
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1997
1997
The structure of a complex between a hexapeptide-based inhibitor, MVT-101, and the chemically synthesized (Aba 67,95,167,195; Aba… (More)
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1997
1997
Six models of the catalytic site of HIV-1 protease complexed with a reduced peptide inhibitor, MVT-101, were investigated. These… (More)
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1996
1996
Empirical free energy calculations of HIV-1 protease crystallographic complexes based on the developed knowledge-based ligand… (More)
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1995
1995
HIV-1 aspartic protease (PR) is a promising target for acquired immunodeficiency syndrome (AIDS) therapy, and the development of… (More)
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1994
1994
The X-ray crystal-structure-based design, synthesis, computational evaluation, and activity of a novel class of HIV protease… (More)
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1993
1993
Rational ligand design is a complex problem that can be divided into three parts: the search for optimal positions and… (More)
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1993
1993
An analogue of "HIV-1 protease" was designed in which the ability to donate important water-mediated hydrogen bonds to substrate… (More)
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1992
1992
Crystallographic structures of HIV protease with three different peptide-mimetic inhibitors were subjected to energy minimization… (More)
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