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MUS81 gene

Known as: MUS81 Structure-Specific Endonuclease Subunit Gene, MUS81, S. CEREVISIAE, HOMOLOG OF, SLX3, YEAST, HOMOLOG OF 
This gene plays a role in the metabolism of branched DNA structures.
National Institutes of Health

Related topics

Related topics

4 relations
Catabolic ProcessDNA Maintenance ProcessHydrolysisMUS81 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The DNA translocase RAD5A acts independently of the other main DNA repair pathways, and requires both its ATPase and RING domain for activity in Arabidopsis thaliana
Multiple pathways exist to repair DNA damage induced by methylating and crosslinking agents in Arabidopsis thaliana. The SWI2… 
2014
2014
The Arabidopsis thaliana Homolog of the Helicase RTEL1 Plays Multiple Roles in Preserving Genome Stability[C][W]
A helicase is required to preserve genome stability in plants, which is likely due to its role in destabilizing various types of… 
Highly Cited
2012
Highly Cited
2012
The Mre11 Nuclease Is Critical for the Sensitivity of Cells to Chk1 Inhibition
The Chk1 kinase is required for the arrest of cell cycle progression when DNA is damaged, and for stabilizing stalled replication… 
2011
2011
Three Structure-Selective Endonucleases Are Essential in the Absence of BLM Helicase in Drosophila
DNA repair mechanisms in mitotically proliferating cells avoid generating crossovers, which can contribute to genome instability… 
2011
2011
Inactivation of Chk2 and Mus81 Leads to Impaired Lymphocytes Development, Reduced Genomic Instability, and Suppression of Cancer
Chk2 is an effector kinase important for the activation of cell cycle checkpoints, p53, and apoptosis in response to DNA damage… 
2007
2007
Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae.
2007
2007
Functional interplay of p53 and Mus81 in DNA damage responses and cancer.
Mus81 plays an integral role in the maintenance of genome stability and DNA repair in mammalian cells. Deficiency of Mus81 in… 
2007
2007
The novel gene mus7(+) is involved in the repair of replication-associated DNA damage in fission yeast.
Highly Cited
2003
Highly Cited
2003
RNA interference inhibition of Mus81 reduces mitotic recombination in human cells.
Mus81 is a highly conserved endonuclease with homology to the XPF subunit of the XPF-ERCC1 complex. In yeast Mus81 associates… 
Highly Cited
2003
Highly Cited
2003
Mus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cells.
Mus81 is a highly conserved substrate specific endonuclease. Human Mus81 cleaves Holliday junctions, replication forks, and 3… 
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