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MUS81 gene

Known as: MUS81 Structure-Specific Endonuclease Subunit Gene, MUS81, S. CEREVISIAE, HOMOLOG OF, SLX3, YEAST, HOMOLOG OF 
This gene plays a role in the metabolism of branched DNA structures.
National Institutes of Health

Related topics

Related topics

4 relations
Catabolic ProcessDNA Maintenance ProcessHydrolysisMUS81 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Replication stress activates DNA repair synthesis in mitosis
Oncogene-induced DNA replication stress has been implicated as a driver of tumorigenesis. Many chromosomal rearrangements… 
Review
2008
Review
2008
Structural and functional relationships of the XPF/MUS81 family of proteins.
Proteins belonging to the XPF/MUS81 family play important roles in the repair of DNA lesions caused by UV-light or DNA cross… 
Highly Cited
2008
Highly Cited
2008
Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease
The DNA structure-selective endonuclease Mus81-Mms4/Eme1 is a context-specific recombination factor that supports DNA replication… 
Highly Cited
2007
Highly Cited
2007
The Role of AtMUS81 in Interference-Insensitive Crossovers in A. thaliana
MUS81 is conserved among plants, animals, and fungi and is known to be involved in mitotic DNA damage repair and meiotic… 
Highly Cited
2006
Highly Cited
2006
Single Holliday Junctions Are Intermediates of Meiotic Recombination
Review
2004
Review
2004
The Mus81 solution to resolution: generating meiotic crossovers without Holliday junctions.
During meiosis, recombination between homologous chromosomes creates a physical connection that is necessary for proper… 
Highly Cited
2002
Highly Cited
2002
Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication
Toxic recombination events are detected in vegetative Saccharomyces cerevisiae cells through negative growth interactions between… 
Highly Cited
2001
Highly Cited
2001
Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae.
The Saccharomyces cerevisiae Sgs1 protein is a member of the RecQ family of DNA helicases and is required for genome stability… 
Highly Cited
2001
Highly Cited
2001
Human Mus81-associated endonuclease cleaves Holliday junctions in vitro.
Highly Cited
2000
Highly Cited
2000
Damage Tolerance Protein Mus81 Associates with the FHA1 Domain of Checkpoint Kinase Cds1
ABSTRACT Cds1, a serine/threonine kinase, enforces the S-M checkpoint in the fission yeast Schizosaccharomyces pombe. Cds1 is… 
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