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MUC17 gene

Known as: MUC17, MUCIN 17, mucin 17, cell surface associated 
 
National Institutes of Health

Papers overview

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2019
2019
Epigenetic downregulation of MUC17 by H. pylori infection facilitates NF-κB-mediated expression of CEACAM1-3S in human gastric cancer
Background and aimsHelicobacter pylori invades the mucosal barrier and infects the mucins of gastric epithelial cells. However… Expand
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2019
2019
Analysis of TGCA data reveals genetic and epigenetic changes and biological function of MUC family genes in colorectal cancer.
Aim: Few studies focused on functions and regulatory networks of MUC family members in colorectal cancer based on comprehensive… Expand
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Highly Cited
2018
Highly Cited
2018
Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.
BACKGROUND & AIMS Biliary tract cancers (BTCs) are clinically and pathologically heterogeneous and respond poorly to treatment… Expand
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2015
2015
Genetic variations of MUC17 are associated with endometriosis development and related infertility
BackgroundGenetic alterations of mucin genes, such as MUC2 and MUC4, were previously identified to be associated with… Expand
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2013
2013
Carbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytes.
We have reported that transmembrane mucin MUC17 binds PDZ protein PDZK1, which retains MUC17 apically in enterocytes. MUC17 and… Expand
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2012
2012
Expression of MUC17 Is Regulated by HIF1α-Mediated Hypoxic Responses and Requires a Methylation-Free Hypoxia Responsible Element in Pancreatic Cancer
MUC17 is a type 1 membrane-bound glycoprotein that is mainly expressed in the digestive tract. Recent studies have demonstrated… Expand
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2011
2011
Muc17 protects intestinal epithelial cells from enteroinvasive E. coli infection by promoting epithelial barrier integrity.
The membrane-bound mucin MUC17 (mouse homolog Muc3) is highly expressed on the apical surface of intestinal epithelia and is… Expand
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2011
2011
Changes in the mucosal barrier during acute and chronic Trichuris muris infection
The intestinal mucosal barrier, part of the innate immune defence, is responsive to the external environment and changes in… Expand
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2010
2010
Molecular markers associated with lymph node metastasis in pancreatic ductal adenocarcinoma by genome-wide expression profiling.
Lymph node metastasis (LNM) is the most important prognostic factor in patients undergoing surgical resection of pancreatic… Expand
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2010
2010
Genome wide analysis of the bovine mucin genes and their gastrointestinal transcription profile
BackgroundMucins are large glycoproteins implicated in protection of all mucosal surfaces. In humans and rodents, the mucin gene… Expand
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