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Background and aimsHelicobacter pylori invades the mucosal barrier and infects the mucins of gastric epithelial cells. However… Expand Aim: Few studies focused on functions and regulatory networks of MUC family members in colorectal cancer based on comprehensive… Expand BACKGROUND & AIMS
Biliary tract cancers (BTCs) are clinically and pathologically heterogeneous and respond poorly to treatment… Expand Development of biomarkers that detect early stage resectable premalignant lesions of colon can provide critical aid in the… Expand BackgroundGenetic alterations of mucin genes, such as MUC2 and MUC4, were previously identified to be associated with… Expand We have reported that transmembrane mucin MUC17 binds PDZ protein PDZK1, which retains MUC17 apically in enterocytes. MUC17 and… Expand MUC17 is a type 1 membrane-bound glycoprotein that is mainly expressed in the digestive tract. Recent studies have demonstrated… Expand The intestinal mucosal barrier, part of the innate immune defence, is responsive to the external environment and changes in… Expand The membrane-bound mucin MUC17 (mouse homolog Muc3) is highly expressed on the apical surface of intestinal epithelia and is… Expand Lymph node metastasis (LNM) is the most important prognostic factor in patients undergoing surgical resection of pancreatic… Expand