MTF-1 Inhibitor APTO-253 HCl

Known as: 2-(6-Fluoro-2-methyl-1H-indol-3-yl)-1H-imidazo[4,5-f][1,10]phenanthroline Hydrochloride, APTO-253 HCl

The hydrochloride salt of a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF…

National Institutes of Health

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2009

Abstract The metal-responsive transcription factor-1 (MTF-1) protein is a highly conserved zinc finger protein that is essential…