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MTF-1 Inhibitor APTO-253 HCl

Known as: 2-(6-Fluoro-2-methyl-1H-indol-3-yl)-1H-imidazo[4,5-f][1,10]phenanthroline Hydrochloride, APTO-253 HCl 
The hydrochloride salt of a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF… 
National Institutes of Health

Related topics

Related topics

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NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
New ruthenium polypyridyl complexes functionalized with fluorine atom or furan: Synthesis, DNA-binding, cytotoxicity and antitumor mechanism studies.
2020
2020
Switch-on effect on conformation-specific arylamine–DNA adduct by cyclometalated Ir(III) complexes
Arylamines are known to form covalent-DNA adducts upon metabolic activation. These covalent adducts adopt different… 
2019
2019
DNA binding, photocleavage, antimicrobial and cytotoxic properties of Ru(II) polypyridyl complexes containing BOPIP ligand, (BOPIP = {2-(4-(benzyloxy) phenyl)-1H-imidazo [4,5-f] [1,2]phenanthroline})
Abstract A novel ligand BOPIP (BOPIP = {2-(4-(benzyloxy)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline}) and its mononuclear Ru(II… 
2019
2019
Selective recognition of DNA defects by cyclometalated Ir(iii) complexes.
Selective detection of DNA defects is an attractive approach for early detection of various tumors and diseases. Ru(ii), Rh(iii… 
2017
2017
A highly sensitive and selective visible-light excitable luminescent probe for singlet oxygen based on a dinuclear ruthenium complex.
A dinuclear Ru(ii) complex of [(bpy)2Ru(H2ipaip)Ru(bpy)2]Cl4 {bpy = 2,2'-bipyridine, H2ipaip = 2-(9-(1H-imidazo[4,5-f][1,10… 
2013
2013
The effects of linear assembly of two carbazole groups on acid-base and DNA-binding properties of a ruthenium(II) complex.
2012
2012
Enhanced light-harvesting capability by phenothiazine in ruthenium sensitizers with superior photovoltaic performance
This paper reports on the design and synthesis of two new ruthenium dyes [Ru(dcbpy)(potip)(NCS)2] (JF-3, dcbpy = 4,4… 
2011
2011
A Ru(II) complex with 2-(4-(methylsulfonyl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline: synthesis, characterization, and acid-base and DNA-binding properties.
Highly Cited
2010
Highly Cited
2010
A triphenylamine-grafted imidazo[4,5-f][1,10]phenanthroline ruthenium(II) complex: acid-base and photoelectric properties.
A new heteroleptic ruthenium(II) complex of [Ru(Hipdpa)(Hdcbpy)(NCS)(2)](-).0.5H(+).0.5[N(C(4)H(9))(4)](+) Ru(Hipdpa) {where… 
2000
2000
The effects of protein kinase C and calmodulin kinase II inhibitors on vestibular compensation in the guinea pig
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