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MTBP gene

Known as: MDM2-BINDING PROTEIN, MTBP, MDM2 binding protein 
 
National Institutes of Health

Papers overview

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2017
2017
Cancer-induced bone pain can severely compromise the life quality of patients, while tolerance limits the use of opioids in the… Expand
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2015
2015
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with increasing incidence. Despite curative surgical… Expand
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2014
2014
Despite its involvement in most human cancers, MYC continues to pose a challenge as a readily tractable therapeutic target. Here… Expand
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2013
2013
Murine double minute (MDM2) binding protein (MTBP) has been implicated in cancer progression. Here, we demonstrate one mechanism… Expand
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2011
2011
BACKGROUND Recent genetic studies have implicated p53 mutation as a significant risk factor for therapeutic failure in squamous… Expand
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2011
2011
Murine double minute 2 (MDM2) binding protein (MTBP) has been implicated in tumor cell proliferation, but the underlying… Expand
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2010
2010
Mdm2 binding protein (MTBP) has been implicated in cell-cycle arrest and the Mdm2/p53 tumor suppressor pathway through its… Expand
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2008
2008
Mdm2 inhibits the function of the p53 tumor suppressor. Mdm2 is overexpressed in many tumors with wild-type p53 suggesting an… Expand
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2005
2005
p53 is a critical coordinator of a wide range of stress responses. To facilitate a rapid response to stress, p53 is produced… Expand
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Highly Cited
2000
Highly Cited
2000
The MDM2 protein, through its interaction with p53, plays an important role in the regulation of the G(1) checkpoint of the cell… Expand
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