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MTBP gene

Known as: MDM2-BINDING PROTEIN, MTBP, MDM2 binding protein 
National Institutes of Health

Papers overview

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2019
2019
Accurate genome duplication underlies genetic homeostasis. Metazoan Mdm2 binding protein (MTBP) forms a main regulatory platform… 
2017
2017
MTBP, the partner of Treslin, contains a novel DNA-binding domain that associates with double-stranded DNA and G-quadruplex DNA… 
2014
2014
Despite its involvement in most human cancers, MYC continues to pose a challenge as a readily tractable therapeutic target. Here… 
2014
2014
Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer commonly resistant to therapeutics that… 
Highly Cited
2013
Highly Cited
2013
Murine double minute (MDM2) binding protein (MTBP) has been implicated in cancer progression. Here, we demonstrate one mechanism… 
2010
2010
Mdm2 binding protein (MTBP) has been implicated in cell-cycle arrest and the Mdm2/p53 tumor suppressor pathway through its… 
2008
2008
Mdm2 inhibits the function of the p53 tumor suppressor. Mdm2 is overexpressed in many tumors with wild-type p53 suggesting an… 
Highly Cited
2005
Highly Cited
2005
ABSTRACT p53 is a critical coordinator of a wide range of stress responses. To facilitate a rapid response to stress, p53 is… 
2003
2003
In previous work, we identified a telomeric DNA-binding protein (termed telomere-membrane binding protein, MTBP) in the envelope… 
Highly Cited
2000
Highly Cited
2000
The MDM2 protein, through its interaction with p53, plays an important role in the regulation of the G1 checkpoint of the cell…