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MTA2 gene

Known as: PID, METASTASIS-ASSOCIATED 1-LIKE 1, MTA1-L1 
This gene plays a role in chromatin modification.
National Institutes of Health

Related topics

Related topics

1 relation
chromatin remodeling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Regulation of MicroRNAs by Natural Agents: New Strategies in Cancer Therapies
MicroRNAs (miRNAs) are short noncoding RNA which regulate gene expression by messenger RNA (mRNA) degradation or translation… 
Highly Cited
2014
Highly Cited
2014
Targeted NGS: A Cost-Effective Approach to Molecular Diagnosis of PIDs
Background: Primary immunodeficiencies (PIDs) are a diverse group of disorders caused by multiple genetic defects. Obtaining a… 
Highly Cited
2010
Highly Cited
2010
The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage
NuRD is recruited to DNA double-strand breaks, where it promotes RNF8/RNF168 histone ubiquitylation and accumulation of DNA… 
Highly Cited
2006
Highly Cited
2006
Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells.
Estrogen receptor (ER)alpha activity is controlled by the balance of coactivators and corepressors contained within cells that… 
Highly Cited
2004
Highly Cited
2004
MBD3L1 Is a Transcriptional Repressor That Interacts with Methyl-CpG-binding Protein 2 (MBD2) and Components of the NuRD Complex*
Methyl-CpG-binding domain proteins 2 and 3 (MBD2 and MBD3) are transcriptional repressors that contain methyl-CpG binding domains… 
Highly Cited
2003
Highly Cited
2003
The Metastasis-associated Proteins 1 and 2 Form Distinct Protein Complexes with Histone Deacetylase Activity*
The metastasis-associated protein MTA1 has been shown to express differentially to high levels in metastatic cells. MTA2, which… 
Highly Cited
2001
Highly Cited
2001
CoREST is an integral component of the CoREST- human histone deacetylase complex.
Here we describe the components of a histone deacetylase (HDAC) complex that we term the CoREST-HDAC complex. CoREST-HDAC is… 
Highly Cited
2000
Highly Cited
2000
Deacetylation of p53 modulates its effect on cell growth and apoptosis
The p53 tumour suppressor is a transcriptional factor whose activity is modulated by protein stability and post-translational… 
Highly Cited
1999
Highly Cited
1999
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.
ATP-dependent nucleosome remodeling and core histone acetylation and deacetylation represent mechanisms to alter nucleosome… 
Highly Cited
1999
Highly Cited
1999
Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4.
Ataxia telangiectasia mutated (ATM)- and Rad3-related protein (ATR) is a phosphatidylinositol-kinase (PIK)-related kinase that… 
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