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MRZ-99030

National Institutes of Health

Papers overview

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2015
2015
MRZ-99030 – A novel modulator of Aβ aggregation: II – Reversal of Aβ oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice
2014
2014
Effect of the Aβ Aggregation Modulator MRZ-99030 on Retinal Damage in an Animal Model of Glaucoma
Several lines of evidence suggest that there are similarities in the pathomechanisms of glaucoma and Alzheimer’s disease, and… 
2014
2014
MRZ-99030 - a novel inhibitor of beta-amyloid (AB) aggregation reverses AB oligomer-induced deficits in long-term potentiation (LTP) and cognition in rodents
2014
2014
Ocular and Systemic Distribution of the Developmental Glaucoma and Dry AMD drug MRZ-99030 in Pigmented Mouse, Rat, Rabbit, and Non-Human Primate
2014
2014
MRZ-99030 - a novel modulator of β-amyloid (Aβ) aggregation for the topical neuroprotective treatment of glaucoma and age-related macular degeneration (AMD)
2013
2013
Ocular and systemic distribution of MRZ-99030 in pigmented mouse, rat, rabbit and non-human primate by quantitative tissue analysis
Purpose The ocular tissue distribution and systemic pharmacokinetics of MRZ-99030 was determined after single or repeated topical… 
2013
2013
Topical administration of MRZ-99030, a β-amyloid aggregation modulator, protects retinal ganglion cells and axons in a rodent model of glaucoma
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