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MRT67307
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Cyclobutanes
Morpholines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Reversal of CYLD phosphorylation as a novel therapeutic approach for adult T-cell leukemia/lymphoma (ATLL)
X. Xu
,
M. Kalac
,
+10 authors
A. Ting
Cell Death & Disease
2020
Corpus ID: 211028754
Adult T-cell leukemia/lymphoma (ATLL) is a malignancy of mature T cells associated with chronic infection by human T-cell…
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2020
2020
Polyinosinic-Polycytidylic Acid Induces CXCL1 Expression in Cultured hCMEC/D3 Human Cerebral Microvascular Endothelial Cells
Yuchen Li
,
T. Imaizumi
,
+4 authors
H. Ohkuma
Neuroimmunomodulation
2020
Corpus ID: 215793259
Objective: Brain microvascular endothelial cells are integral components of the blood-brain barrier and play a role in protecting…
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2018
2018
Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies—T Cell Receptor-Induced CYLD Phosphorylation by IKKε/TBK1 as a Case Study
Marie Lork
,
M. Kreike
,
J. Staal
,
R. Beyaert
Front. Cell Dev. Biol.
2018
Corpus ID: 4714848
CYLD is a deubiquitinating enzyme that plays a crucial role in immunity and inflammation as a negative regulator of NF-κB…
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2018
2018
Baicalein protects against endothelial cell injury by inhibiting the TLR4/NF-κB signaling pathway
C. Wan
,
Man Xu
,
+4 authors
Q. Tang
Molecular medicine reports
2018
Corpus ID: 4745389
The involvement of vascular endothelial injury with the pathophysiological process of heart failure has been identified…
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2017
2017
Abstract 3460: TBK1 regulates mitotic progression by modulating spindle assembly checkpoint in cancer cells
Neha Jaiswal
,
S. Pillai
,
Namrata Bora-Singhal
,
S. Chellappan
2017
Corpus ID: 80250307
TANK Binding Kinase 1 (TBK1) is a non-canonical IkB kinase that contributes to KRAS-driven lung cancer. It is activated by…
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Highly Cited
2015
Highly Cited
2015
Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy*
Katy J. Petherick
,
Owen J. L. Conway
,
+4 authors
I. Ganley
The Journal of Biological Chemistry
2015
Corpus ID: 11180646
Background: Autophagy is an intracellular lysosomal degradation pathway implicated in many diseases, but there are currently no…
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Highly Cited
2011
Highly Cited
2011
Novel cross-talk within the IKK family controls innate immunity.
K. Clark
,
M. Peggie
,
+6 authors
P. Cohen
The Biochemical journal
2011
Corpus ID: 34373578
Members of the IKK {IκB [inhibitor of NF-κB (nuclear factor κB)] kinase} family play a central role in innate immunity by…
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