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MRS 2395

Known as: MRS-2395, MRS2395 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Potentiation of TRAP-6-induced platelet dense granule release by blockade of P2Y12 signaling with MRS2395
Abstract The release of ADP from platelet dense granules and its binding to platelet P2Y12 receptors is key to amplifying the… 
2017
2017
P2Y12 receptor-mediated activation of spinal microglia and p38MAPK pathway contribute to cancer-induced bone pain
Background Cancer-induced bone pain (CIBP) is one of the most challenging clinical problems due to a lack of understanding the… 
2017
2017
Interaction between calcitonin gene‐related peptide‐immunoreactive neurons and satellite cells via P2Y12R in the trigeminal ganglion is involved in neuropathic tongue pain in rats
The P2Y12 receptor expressed in satellite cells of the trigeminal ganglion is thought to contribute to neuropathic pain. The… 
2017
2017
P2Y12 and P2Y13 receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia
Objective P2 receptors have been implicated in the release of neurotransmitter and pro-inflammatory cytokines due to their… 
2016
2016
Involvement of Microglial P2Y12 Signaling in Tongue Cancer Pain
To elucidate if microglial P2Y12 receptor (P2Y12R) mechanisms are involved in the trigeminal spinal subnucleus caudalis (Vc; also… 
2016
2016
P2Y13 receptors mediate presynaptic inhibition of acetylcholine release induced by adenine nucleotides at the mouse neuromuscular junction
2014
2014
[Effects of intrathecal injection P2Y12 receptor inhibitor on interleukin-1 beta and interleukin-6 in spinal cord of rat bone cancer pain model].
OBJECTIVE To explore the roles of P2Y12 receptor (P2Y12R) in bone cancer pain by observing the changes of inflammatory cytokines… 
Highly Cited
2012
Highly Cited
2012
Satellite glial cell P2Y12 receptor in the trigeminal ganglion is involved in lingual neuropathic pain mechanisms in rats
BackgroundIt has been reported that the P2Y12 receptor (P2Y12R) is involved in satellite glial cells (SGCs) activation… 
2012
2012
[Influence of P2Y12 receptor inhibitor on pain threshold and spinal p38MAPK in rat bone cancer pain model].
OBJECTIVE To investigate the role of P2Y12 receptor in rat bone cancer pain model and its influence on p38MAPK (Mitogen-activated… 
Highly Cited
2010
Highly Cited
2010
A comparative analysis of the activity of ligands acting at P2X and P2Y receptor subtypes in models of neuropathic, acute and inflammatory pain
Background and purpose:  This study was undertaken to compare the analgesic activity of antagonists acting at P2X1, P2X7, and… 
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