MME gene

Known as: CD10, CALLA, MME 
This gene is involved in the inactivation of peptide hormones.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Clinical trials in heart failure have focused on the improvement in symptoms or decreases in the risk of death and… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Heart failure with preserved ejection fraction is associated with substantial morbidity and mortality, but effective… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND LCZ696 is a first-in-class inhibitor of the angiotensin II receptor and neprilysin. We aimed to establish whether the… (More)
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Highly Cited
2010
Highly Cited
2010
Angiotensin receptor blockade and neprilysin (NEP) inhibition together offer potential benefits for the treatment of hypertension… (More)
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Review
2007
Review
2007
Animal models aim to replicate the symptoms, the lesions or the cause(s) of Alzheimer disease. Numerous mouse transgenic lines… (More)
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Highly Cited
2005
Highly Cited
2005
Amyloid beta-peptide (Abeta), which plays a central role in Alzheimer's disease, is generated by presenilin-dependent gamma… (More)
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Highly Cited
2004
Highly Cited
2004
A local increase in amyloid-beta peptide (Abeta) is closely associated with synaptic dysfunction in the brain in Alzheimer's… (More)
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Highly Cited
2003
Highly Cited
2003
Converging evidence suggests that the accumulation of cerebral amyloid beta-protein (Abeta) in Alzheimer's disease (AD) reflects… (More)
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Highly Cited
2003
Highly Cited
2003
The degenerative process of Alzheimer's disease is linked to a shift in the balance between amyloid-beta (Abeta) production… (More)
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Highly Cited
2001
Highly Cited
2001
Neprilysin is an enzyme capable of degrading beta-amyloid protein. We measured neprilysin mRNA and protein levels in brain and… (More)
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