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MLN3897

 
National Institutes of Health

Papers overview

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2016
2016
UNLABELLED MLN3897 is a small molecule antagonist of the C-C chemokine receptor-1. Since preclinical studies showed that the… Expand
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2010
2010
A novel in vitro model was recently developed in our laboratories for the prediction of magnitude of clinical pharmacokinetic… Expand
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Review
2010
Review
2010
The identification of chemokines and their receptors as potent mediators of leukocyte infiltration raised interest in the… Expand
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2009
2009
OBJECTIVE To assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of the CC chemokine receptor CCR1 antagonist… Expand
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Highly Cited
2007
Highly Cited
2007
The interaction between osteoclasts (OCs) and multiple myeloma (MM) cells plays a key role in the pathogenesis of MM-related… Expand
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2006
2006
Osteolytic lesions are a hallmark of myeloma bone disease and other metastatic cancers, resulting in significant morbidity. In… Expand
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2006
2006
Multiple Myeloma (MM) is characterized by increased osteoclasts (OC) activity leading to severe bone disease. Several inducers of… Expand
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