MKC-1

An orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2016
01219992016

Papers overview

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2016
2016
The research was a development model in teaching of creative writing short story based siri’na pace. The purpose of this study… (More)
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2014
2014
Raf kinase inhibitor protein (RKIP) is a member of the phosphatidylethanolamine-binding-protein (PEBP) family that modulates the… (More)
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Review
2012
Review
2012
PI3K/AKT/mTOR pathway is a crucial mediator of tumor progression. As the PI3K/Akt pathway is heavily deregulated in breast cancer… (More)
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2011
2011
Background MKC-1 is an orally available cell cycle inhibitor with downstream targets that include tubulin and the importin… (More)
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2010
2010
Background MKC-1 is an oral cell-cycle inhibitor with broad antitumor activity in preclinical models. Clinical studies… (More)
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2010
2010
Bisindolylmaleimide MKC-1 (formerly known as Ro 31-7453) is a novel, orally active, small-molecule, cell cycle inhibitor with… (More)
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2009
2009
5577 Background: MKC-1 is a novel oral cell cycle inhibitor with preclinical activity in xenograft models of human ovarian and… (More)
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2009
2009
e19005 Background: MKC-1 is a novel oral cell cycle inhibitor with preclinical activity against NSCLC cell lines including multi… (More)
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1999
1999
Keratin 14 (K14) is believed to play a pivotal role in the maintenance of epidermal cell shape and contributing to their… (More)
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