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MK 927

Known as: MK 0927, MK-0927, MK-927 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

sezolamide

Papers overview

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1992
1992
Uptake and Stereoselective Binding of the Enantiomers of MK-927, a Potent Carbonic Anhydrase Inhibitor, by Human Erythrocytes in Vitro
MK-927 [5,6-dihydro-4H-4(isobutylamino)thieno(2,3-B)thiopyran-2-sulfonamide-7.7 dioxide], a potent carbonic anhydrase inhibitor… 
1991
1991
Evaluation of a topically administered carbonic anhydrase inhibitor (MK-927) in normotensive and glaucomatous beagles.
A new topically administered anhydrase inhibitor, MK-927, was evaluated for its ocular hypotensive activity in normotensive and… 
1991
1991
Multiple-dose, dose-response relationship for the topical carbonic anhydrase inhibitor MK-927.
The multiple-dose, dose-response curve of MK-927 was studied in a five-center, double-masked, randomized, placebo-controlled… 
1991
1991
Absence of metabolic effects of the topical carbonic anhydrase inhibitors MK‐927 and sezolamide during two‐week ocular administration to normal subjects
Potential systemic effects of the racemic carbonic anhydrase inhibitor MK‐927 and its S‐enantiomer, sezolamide hydrochloride… 
1990
1990
MK-927: a topical carbonic anhydrase inhibitor. Dose response and duration of action.
The dose response to a single topical administration of the carbonic anhydrase inhibitor MK-927 was investigated in 24 patients… 
1990
1990
MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor.
MK-927 (dl-5,6-dihydro-4-(2-methylpropylamino)-4H-thieno(2,3b)thiopyra n-2-sulfonamide-7,7-dioxide hydrochloride) is a water… 
1990
1990
MK-927, a topical carbonic anhydrase inhibitor. Dose response and reproducibility.
We investigated the dose-response and reproducibility of the intraocular pressure-lowering effect of MK-927 in ocular… 
1990
1990
The effect of MK-927, a topical carbonic anhydrase inhibitor, on IOP in glaucomatous monkeys.
MK-927 is a water soluble, potent inhibitor of human carbonic anhydrase (CA) II in vitro. Topical administration of MK-927… 
1989
1989
MK-927: a topically effective carbonic anhydrase inhibitor in patients.
The effects on intraocular pressure of the novel topical carbonic anhydrase inhibitor MK-927 were investigated for the first time… 
1988
1988
Local tolerance and activity of MK-927, a novel topical carbonic anhydrase inhibitor.
A three-dose, randomized, double-masked, parallel, placebo-controlled ocular tolerance study was undertaken in 12 healthy, normal… 
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