MK-7123

 
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
RATIONALE An antagonist (MK-7123) of the cytokine receptor CXCR2 reduces neutrophil chemotaxis and thus may alleviate airway… Expand
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2015
2015
The CXCR2 antagonist MK-7123 causes dose-dependent reductions in absolute neutrophil counts (ANC) and decreases neutrophil tissue… Expand
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2015
2015
This study describes an analytical method for bioaffinity and selectivity assessment of CXCR2 antagonists and their metabolites… Expand
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2015
2015
Neutrophils provide innate immune defence against microbes such as bacteria. Neutrophilic airway inflammation is a characteristic… Expand
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2013
2013
Antagonism of the chemokine receptor CXCR2 inhibits neutrophil trafficking and may thus be therapeutic in patients with chronic… Expand
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