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MK-1439

 
National Institutes of Health

Papers overview

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2019
2019
Abstract Absorption, distribution, metabolism and elimination of doravirine (MK-1439), a novel non-nucleoside reverse… Expand
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2019
2019
Aim: A method to quantitate Doravirine (MK-1439) in human plasma has been developed to support human clinical trials designed to… Expand
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2018
2018
  • N. Sluis-Cremer
  • Proceedings of the National Academy of Sciences
  • 2018
  • Corpus ID: 22557293
The nonnucleoside reverse transcriptase (RT) inhibitors (NNRTIs) are small molecules that bind to HIV-1 RT at a site distinct… Expand
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2017
2017
RATIONALE During the development of a novel synthetic route to doravirine (1), a human immunodeficiency type 1 virus (HIV-1… Expand
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2016
2016
IntroductionDoravirine, a non-nucleoside reverse-transcriptase inhibitor in development for the treatment of patients with human… Expand
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2014
2014
Doravirine (DOR) is an investigational NNRTI (aka MK‐1439) that retains activity against common NNRTI‐resistant mutants. We have… Expand
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Highly Cited
2014
Highly Cited
2014
ABSTRACT Doravirine (DOR, formerly known as MK-1439) is a human immunodeficiency type 1 virus (HIV-1) nonnucleoside reverse… Expand
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2014
2014
The optimization of a novel series of non-nucleoside reverse transcriptase inhibitors (NNRTI) led to the identification of… Expand
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Highly Cited
2013
Highly Cited
2013
ABSTRACT Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are a mainstay of therapy for treating human immunodeficiency… Expand
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Review
2012
Review
2012
  • M. Saag
  • Topics in antiviral medicine
  • 2012
  • Corpus ID: 788493
Numerous investigational antiretroviral agents are in clinical development. Among them are festinavir (BMS986001), a thymidine… Expand
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