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MK-1439

National Institutes of Health

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DORAVIRINE

Papers overview

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2019
2019
Determination of Doravirine in human plasma using liquid-liquid extraction and HPLC-MS/MS.
Aim: A method to quantitate Doravirine (MK-1439) in human plasma has been developed to support human clinical trials designed to… 
2017
2017
Unusual (+/-)-electrospray ionization induced fragmentation: Structural elucidation of an in-process synthetic intermediate of doravirine (MK-1439) using liquid chromatography/high-resolution tandem…
RATIONALE During the development of a novel synthetic route to doravirine (1), a human immunodeficiency type 1 virus (HIV-1… 
2017
2017
Unusual (+/‐)‐Electrospray Ionization Induced Fragmentation: Structural Elucidation of an In‐process Synthetic Intermediate of Doravirine (MK‐1439) Using LC/HRMS/MS and 2D‐NMR
2017
2017
Erratum to: A Two-Way Steady-State Pharmacokinetic Interaction Study of Doravirine (MK-1439) and Dolutegravir
2014
2014
New ARV drugs
There are 28 approved antiretroviral drugs for the treatment of HIV infection; combinations of these drugs clearly change the… 
2014
2014
Oral PresentationAbstract O434 Forty-eight-week efficacy and safety and early CNS tolerability of doravirine (MK-1439), a novel NNRTI, with TDF/FTC in ART-naive HIV-positive patients
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