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MK 1256
Known as:
MK-1256
, MK1256
National Institutes of Health
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2019
2019
Suppression of cathepsin K biomarker in synovial fluid as a free-drug–driven process
B. Ma
,
G. Wesolowski
,
+5 authors
L. Lubbers
Journal of Circulating Biomarkers
2019
Corpus ID: 58948762
Cathepsin K (CatK) inhibitors exhibited chondroprotective and pain-reducing effects in animal models, however, improvements were…
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2008
2008
Identification of a nonbasic, nitrile-containing cathepsin K inhibitor (MK-1256) that is efficacious in a monkey model of osteoporosis.
J. Robichaud
,
W. Black
,
+15 authors
S. Crane
Journal of Medicinal Chemistry
2008
Corpus ID: 27953203
Herein, we report on the identification of nonbasic, potent, and highly selective, nitrile-containing cathepsin K (Cat K…
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