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Resume La 11β-hydroxysteroide deshydrogenase de type 1 (11βHSD1) est une enzyme intervenant dans la transformation tissulaire de… Expand AIMS
To characterize pharmacokinetic parameters of MK-0916 and its safety and tolerability in lean, healthy male subjects… Expand The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a target for novel type 2 diabetes and obesity therapies based… Expand OBJECTIVE
Metabolic syndrome (MetS) and Cushing's syndrome share common features. It has been proposed that increased… Expand Aim: We examined the effects of the 11β‐hydroxysteroid dehydrogenase type 1 (HSD1) inhibitor, MK‐0916, on the multiple components… Expand 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) may be involved in several abnormalities associated with the metabolic… Expand