MK-0657
National Institutes of Health
Papers overview
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Traditional pharmacological treatments for depression have a delayed therapeutic onset, ranging from several weeks to months, and…
Objectives Blockade of N-methyl-D-aspartate receptors containing the NR2B subunit has been shown to be therapeutic in animal…
Current pharmacotherapies for major depressive disorder (MDD) have a distinct lag of onset that can prolong distress and…
BACKGROUND
Considering the ample evidence of involvement of the glutamate system in the pathophysiology of depression, pre…
Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to…
Abstract Converging lines of evidence suggest that the glutamatergic system may play an increasingly important role in the…
The glutamatergic system is thought to contribute to the motor disturbances observed in Parkinson's disease. Blockade of…