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MK-0657

 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Learning objective After participating in this activity, learners should be better able to evaluate the evidence supporting the… Expand
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Review
2018
Review
2018
Traditional pharmacological treatments for depression have a delayed therapeutic onset, ranging from several weeks to months, and… Expand
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2017
2017
Objectives Blockade of N-methyl-D-aspartate receptors containing the NR2B subunit has been shown to be therapeutic in animal… Expand
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Review
2016
Review
2016
Major depression is a common, recurrent mental illness that affects millions of people worldwide. Recently, a unique fast… Expand
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Review
2015
Review
2015
BACKGROUND Considering the ample evidence of involvement of the glutamate system in the pathophysiology of depression, pre… Expand
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2015
2015
N-methyl-D-aspartate (NMDA) receptor antagonists, including open channel blockers and GluN2B receptor subtype selective… Expand
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Review
2015
Review
2015
The need for rapid acting antidepressants is widely recognised. There has been much interest in glutamate mechanisms in major… Expand
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Review
2013
Review
2013
Severe psychiatric disorders such as schizophrenia are related to cognitive and negative symptoms, which often are resistant to… Expand
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Highly Cited
2012
Highly Cited
2012
Converging lines of evidence suggest that the glutamatergic system may play an increasingly important role in the development of… Expand
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2009
2009
The glutamatergic system is thought to contribute to the motor disturbances observed in Parkinson's disease. Blockade of… Expand
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