MK-0524

Known as: MK0524 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2016
02420062016

Papers overview

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2012
2012
OBJECTIVE Nicotinic acid (NA) treatment has been associated with benefits in atherosclerosis that are usually attributed to… (More)
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2012
2012
OBJECTIVE Prostaglandin D2 (PGD2) may exert proinflammatory or antiinflammatory effects in different biologic systems. Although… (More)
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Highly Cited
2008
Highly Cited
2008
Niacin (nicotinic acid) is not optimally used mainly because of flushing, a process mediated primarily by prostaglandin D(2… (More)
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2007
2007
Metabolites of the potent DP antagonist, MK-0524, were generated using in vitro systems including hepatic microsomes and… (More)
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2007
2007
The discovery of the potent and selective prostaglandin D2 (PGD2) receptor (DP) antagonist [(3R)-4-(4-chlorobenzyl)-7-fluoro-5… (More)
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2007
2007
(3R)-4-(4-Chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl acetic acid (MK-0524) is a potent… (More)
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2007
2007
[(3R)-4-(4-Chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopentaindol-3-yl]acetic acid (MK-0524) is a potent… (More)
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2007
2007
MK-0524 is a potent, selective and orally active Prosglandin D(2) Receptor 1 (DP(1)) antagonist currently under clinical… (More)
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Highly Cited
2006
Highly Cited
2006
Nicotinic acid (NA) is commonly used to treat dyslipidemia, but it elicits an adverse effect, termed flushing, which consists of… (More)
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2006
2006
Nasal congestion in allergic rhinitis results from tissue edema and vasodilatation in the nasal mucosa. Of the mediators released… (More)
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