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MIRLET7B gene

Known as: LET7B, LET7, C. ELEGANS, HOMOLOG OF, B, MIRNLET7B 
This gene is involved in the regulation of gene expression and plays a tumor suppressor role in lung carcinoma and melanoma.
National Institutes of Health

Related topics

Related topics

6 relations
Carcinoma of lungHomo sapiensMIRLET7C Pre-miRNAMicroRNAs

Narrower (1)

MIRLET7B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Hsa-let-7b Suppresses Cell Proliferation by Targeting UHRF1 in Melanoma
Abstract UHRF1 promotes melanoma progression by inducing cell proliferation, and is correlated with poor prognosis of melanoma… 
2017
2017
Repression of MicroRNA Function Mediates Inflammation-associated Colon Tumorigenesis.
BACKGROUND & AIMS Little is known about the mechanisms by which chronic inflammation contributes to carcinogenesis, such as the… 
Review
2016
Review
2016
Polymeric Nanocarriers for Delivery of Small Molecules and miRNAs for the Treatment of Liver Fibrosis and Pancreatic Cancer
The aim of this thesis is to develop combination therapy of small molecules and miRNAs for treating liver fibrosis and pancreatic… 
2016
2016
Association between tuberculosis and circulating microRNA hsa-let-7b and hsa-miR-30b: A pilot study in a Chinese population.
2015
2015
MicroRNA let‐7b regulates genomic balance by targeting Aurora B kinase
2014
2014
Identification of miRNAs Expression Profile in Gastric Cancer Using Self-Organizing Maps (SOM)
In this paper, an unsupervised artificial neural network was implemented to identify the patters of specific signatures. The… 
2013
2013
The Jumanjii Histone Demethylase KDM2B controls EZH2 Expression In Myelodysplastic Syndromes (MDS) Via Mir Let-7b (let7b), a Pathway That Is Bypassed By The Histone Methylation Inhibitor DZNep
Background and Hypothesis DNA and histone methylation as well as microRNA (miR) expression are dysregulated in MDS. The histone… 
2013
2013
AKT in Differential miRNA Processing in Prostate Carcinoma
Abstract : Our original hypothesis was AKT regulates the RNA-induced silencing Complex (RISC) activity through the… 
Highly Cited
2012
Highly Cited
2012
Downregulation of HMGA2 by the pan-deacetylase inhibitor panobinostat is dependent on hsa-let-7b expression in liver cancer cell lines.
2011
2011
MicroRNA profile in gastrointestinal stromal tumors (GISTs) and correlation with KIT/PDGFRA kinase genotype.
10056 Background: Gastrointestinal stromal tumors (GISTs) are characterized by oncogenic mutations of KIT and PDGFRA receptors… 
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