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MIR17HG gene

Known as: C13ORF25, LINC00048, miR-17-92a-1 cluster host gene 
This polycistronic gene locus is located in the vicinity of 13q31.3 and is approximately 7 kb in length. This locus encodes at least six microRNA… 
National Institutes of Health

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Related topics

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Homo sapiensSPRYD7 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis*
Background: miR-17/20a are oncogenic microRNAs in human cancers. Results: A p53 kinase DAPK3 was identified as a key target for… 
2014
2014
Association of Plasma MiR-17-92 With Dyslipidemia in Patients With Coronary Artery Disease
AbstractCirculating microRNAs (miRNAs) have already been proposed as sensitive and informative biomarkers for the diagnosis of… 
2013
2013
microRNA miR-17-92 cluster is highly expressed in epidermal Langerhans cells but not required for its development
Langerhans cells (LCs) are bone marrow-derived immature skin-residential dendritic cells (DCs) with a life cycle distinct from… 
2013
2013
Analysis of Transcriptional Regulation of the Human miR-17-92 Cluster; Evidence for Involvement of Pim-1
The human polycistronic miRNA cluster miR-17-92 is frequently overexpressed in hematopoietic malignancies and cancers. Its… 
Review
2013
Review
2013
microRNA biogenesis and senescence
Cellular senescence acts as a physiological barrier against uncontrolled proliferation of cells with potentially harmful… 
2012
2012
MicroRNA 17–92 expressed by a transposone‐based vector changes expression level of cell‐cycle‐related genes
The miR‐17‐92 cluster is composed of seven miRNAs (microRNAs; miR‐17‐5p, miR‐17‐3p, miR‐18a, miR‐19a, miR‐20a, miR‐19b‐1 and miR… 
2012
2012
Spi-1, Fli-1 and Fli-3 (miR-17-92) Oncogenes Contribute to a Single Oncogenic Network Controlling Cell Proliferation in Friend Erythroleukemia
Clonal erythroleukemia developing in susceptible mice infected by Friend virus complex are associated with highly recurrent… 
Highly Cited
2011
Highly Cited
2011
Genomic and Clinical Analysis of Amplification of the 13q31 Chromosomal Region in Alveolar Rhabdomyosarcoma: A Report from the Children's Oncology Group
Purpose: This study determined the molecular characteristics and clinical significance of amplification of the 13q31 chromosomal… 
2010
2010
Pleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19b
Background The histone deacetylase inhibitor ITF2357 has potent cytotoxic activity in multiple myeloma in vitro and has entered… 
2010
2010
Bioinformatics and microarray analysis of microRNA expression profiles of murine embryonic stem cells, neural stem cells induced from ESCs and isolated from E8·5 mouse neural tube
Abstract To better understand whether microRNAs (miRNAs) are involved in the self-renewal of stem cells and fate determination of… 
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