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MHY1485

National Institutes of Health

Papers overview

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2020
2020
Rab1A knockdown represses proliferation and promotes apoptosis in gastric cancer cells by inhibition of mTOR/p70S6K pathway.
2020
2020
Target of rapamycin signaling inhibits autophagy in sea cucumber Apostichopus japonicus.
2019
2019
[Overexpression of autophagy-related gene 3 promotes autophagy and inhibits salinomycin-induced apoptosis in breast cancer MCF-7 cells].
OBJECTIVE To study the effects of the overexpression of autophagy-related gene 3 (ATG3) on autophagy and salinomycin-induced… 
2018
2018
High Glucose Upregulated Vascular Smooth Muscle Endothelin Subtype B Receptors via Inhibition of Autophagy in Rat Superior Mesenteric Arteries.
2018
2018
(−)-Guaiol regulates autophagic cell death depending on mTOR signaling in NSCLC
ABSTRACT (−)-Guaiol, a sesquiterpene alcohol with the guaiane skeleton, has been found in many Chinese medicinal plants and been… 
2018
2018
DNMT1, a Novel Regulator Mediating mTORC1/mTORC2 Pathway-Induced NGF Expression in Schwann Cells
Schwann cells play an important role in maintaining the normal function of peripheral nerves via the secretion of nerve growth… 
2018
2018
T-2 Toxin Exposure Induces Apoptosis in TM3 Cells by Inhibiting Mammalian Target of Rapamycin/Serine/Threonine Protein Kinase(mTORC2/AKT) to Promote Ca2+Production
Although mTOR (the mammalian target of rapamycin) can regulate intracellular free Ca2+concentration in normal cultured podocytes… 
2018
2018
Fluorofenidone inhibits UV‐A induced senescence in human dermal fibroblasts via the mammalian target of rapamycin‐dependent SIRT1 pathway
The aim of this study was to investigate the protective effect of fluorofenidone (5‐methyl‐1‐[3‐fluorophenyl]‐2‐[1H]‐pyridone… 
2017
2017
Mammalian target of rapamycin signaling is a mechanistic link between increased endoplasmic reticulum stress and autophagy in the placentas of pregnancies complicated by growth restriction.
2017
2017
MHY1485 ameliorates UV-induced skin cell damages via activating mTOR-Nrf2 signaling
Ultra Violet (UV)-caused skin cell damage is a main cause of skin cancer. Here, we studied the activity of MHY1485, a mTOR… 
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