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MFN1 gene
Known as:
FLJ20693
, MFN1
, MITOFUSIN 1
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy
Tatsuya Yamada
,
T. Dawson
,
T. Yanagawa
,
M. Iijima
,
H. Sesaki
Autophagy
2019
Corpus ID: 198193492
ABSTRACT The ubiquitination of mitochondrial proteins labels damaged mitochondria for degradation through mitophagy. We recently…
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Review
2017
Review
2017
Control of cell death and mitochondrial fission by ERK1/2 MAP kinase signalling
S. Cook
,
K. Stuart
,
Rebecca H. Gilley
,
Matthew J. Sale
The FEBS Journal
2017
Corpus ID: 4145593
The ERK1/2 signalling pathway is best known for its role in connecting activated growth factor receptors to changes in gene…
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Review
2016
Review
2016
Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity
A. Bertholet
,
T. Delerue
,
+10 authors
P. Belenguer
Neurobiology of Disease
2016
Corpus ID: 12627451
Highly Cited
2016
Highly Cited
2016
Structures of human mitofusin 1 provide insight into mitochondrial tethering
Y. Qi
,
Liming Yan
,
+7 authors
Junjie Hu
Journal of Cell Biology
2016
Corpus ID: 45459180
Mitofusin 1 (MFN1) mediates mitochondrial fusion, but the mechanisms involved are unclear. Qi et al. present the crystal…
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Highly Cited
2015
Highly Cited
2015
Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels
Arnaud Mourier
,
E. Motori
,
+8 authors
N. Larsson
Journal of Cell Biology
2015
Corpus ID: 11703581
Mitofusin 2 plays an unexpected role in maintaining the terpenoid biosynthesis pathway and is necessary for mitochondrial…
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Highly Cited
2012
Highly Cited
2012
Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons.
Seungmin Lee
,
F. Sterky
,
+4 authors
N. Larsson
Human Molecular Genetics
2012
Corpus ID: 7111476
Mitochondrial dysfunction is implicated in aging and degenerative disorders such as Parkinson's disease (PD). Continuous fission…
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Highly Cited
2011
Highly Cited
2011
The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes.
S. Hoppins
,
F. Edlich
,
+4 authors
J. Nunnari
Molecules and Cells
2011
Corpus ID: 21135580
Highly Cited
2010
Highly Cited
2010
Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1
K. Onoguchi
,
K. Onomoto
,
+7 authors
T. Fujita
PLoS Pathogens
2010
Corpus ID: 16862959
In virus-infected cells, RIG-I-like receptor (RLR) recognizes cytoplasmic viral RNA and triggers innate immune responses…
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Review
2008
Review
2008
Mitofusin 2: a mitochondria-shaping protein with signaling roles beyond fusion.
O. M. de Brito
,
L. Scorrano
Antioxidants and Redox Signaling
2008
Corpus ID: 42371323
Mitochondria are central organelles in metabolism, signal transduction, and programmed cell death. To meet their diverse…
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Highly Cited
2008
Highly Cited
2008
Metalloprotease‐mediated OPA1 processing is modulated by the mitochondrial membrane potential
Olwenn Guillery
,
F. Malka
,
+6 authors
M. Rojo
Biology of the Cell
2008
Corpus ID: 45101314
Background information. Human OPA1 (optic atrophy type 1) is a dynamin‐related protein of the mitochondrial IMS (intermembrane…
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