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MEGC-PEG-rMETase

Known as: MEGC-PEG-5000 rMETase conjugate 
National Institutes of Health

Papers overview

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2020
2020
Background/Aim: obesity is a world-wide recalcitrant problem leading to many diseases. Dietary methionine restriction (MR) has… 
2020
2020
Background/Aim: We have recently shown that oral recombinant methionase (o-rMETase) prevents obesity and diabetes onset in mice… 
2020
2020
Background/Aim: We have recently shown that oral recombinant methionase (o-rMETase) prevents obesity in mice on a high-fat (HF… 
2019
2019
Methionine (MET) is a general metabolic therapeutic target in cancer, whereby cancer cells have an elevated requirement for MET… 
2019
2019
The elevated methionine (MET) requirement of cancer cells is termed MET dependence and is possibly the only known general… 
2018
2018
ABSTRACT The elevated methionine (MET) use by cancer cells is termed MET dependence and may be the only known general metabolic… 
2018
2018
Résumé A la fois, moteur du développement et à l’origine des émissions de gaz à effet de serre, le secteur énergétique revêt un… 
Highly Cited
2004
Highly Cited
2004
Methionine depletion by recombinant methioninase (rMETase) has been demonstrated previously to be highly effective in tumor… 
2004
2004
Recombinant methioninase (rMETase) has been shown to target the elevated methionine (MET) dependence of tumor cells and arrest… 
2002
2002