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MEGC-PEG-rMETase

Known as: MEGC-PEG-5000 rMETase conjugate 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

methoxypolyethylene glycol succinimidyl glutarate methioninase conjugate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Oral Recombinant Methioninase Prevents Obesity in Mice on a High-fat Diet
Background/Aim: obesity is a world-wide recalcitrant problem leading to many diseases. Dietary methionine restriction (MR) has… 
2020
2020
Oral Recombinant Methioninase Inhibits Diabetes Onset in Mice on a High-fat Diet
Background/Aim: We have recently shown that oral recombinant methionase (o-rMETase) prevents obesity in mice on a high-fat (HF… 
2020
2020
Oral Recombinant Methioninase Prevents Nonalcoholic Fatty Liver Disease in Mice on a High Fat Diet
Background/Aim: We have recently shown that oral recombinant methionase (o-rMETase) prevents obesity and diabetes onset in mice… 
2019
2019
Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth?
The elevated methionine (MET) requirement of cancer cells is termed MET dependence and is possibly the only known general… 
2019
2019
Safety and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates.
Methionine (MET) is a general metabolic therapeutic target in cancer, whereby cancer cells have an elevated requirement for MET… 
2018
2018
Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer…
ABSTRACT The elevated methionine (MET) use by cancer cells is termed MET dependence and may be the only known general metabolic… 
2007
2007
Accords de partenariat économique et pauvreté au Bénin : une analyse à l'aide d'un MEGC selon le principe de micro-simulation
Resume : L’objet de ce papier est de quantifier les impacts de la mise en œuvre des APE sur la repartition du revenu et la… 
Highly Cited
2004
Highly Cited
2004
PEGylation Confers Greatly Extended Half-Life and Attenuated Immunogenicity to Recombinant Methioninase in Primates
Methionine depletion by recombinant methioninase (rMETase) has been demonstrated previously to be highly effective in tumor… 
2004
2004
Circulating Half-Life of PEGylated Recombinant Methioninase Holoenzyme Is Highly Dose Dependent on Cofactor Pyridoxal-5′-Phosphate
Recombinant methioninase (rMETase) has been shown to target the elevated methionine (MET) dependence of tumor cells and arrest… 
2002
2002
Immunoenzymometric assay for recombinant methioninase in biological fluids.
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