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MEF2D gene

Known as: Myocyte Enhancer Factor 2D Gene, MEF2D, myocyte enhancer factor 2D 
This gene plays a role in muscle and neuronal development.
National Institutes of Health

Related topics

Related topics

7 relations
Homo sapiensOrganogenesisTranscription, GeneticTranscriptional Regulation
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Papers overview

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Highly Cited
2012
Highly Cited
2012
Genome-wide association analysis identifies susceptibility loci for migraine without aura
Migraine without aura is the most common form of migraine, characterized by recurrent disabling headache and associated autonomic… Expand
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Highly Cited
2011
Highly Cited
2011
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
TDP-43 is a predominantly nuclear RNA-binding protein that forms inclusion bodies in frontotemporal lobar degeneration (FTLD) and… Expand
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Highly Cited
2011
Highly Cited
2011
Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients.
The transcription factors in the myocyte enhancer factor 2 (MEF2) family play important roles in cell survival by regulating… Expand
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Highly Cited
2009
Highly Cited
2009
Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy
Chaperone-mediated autophagy controls the degradation of selective cytosolic proteins and may protect neurons against… Expand
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Highly Cited
2008
Highly Cited
2008
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice.
The adult heart responds to excessive neurohumoral signaling and workload by a pathological growth response characterized by… Expand
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Highly Cited
2006
Highly Cited
2006
Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.
Myogenin is required not for the initiation of myogenesis but instead for skeletal muscle formation through poorly understood… Expand
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Highly Cited
2006
Highly Cited
2006
Calpain-Regulated p35/cdk5 Plays a Central Role in Dopaminergic Neuron Death through Modulation of the Transcription Factor Myocyte Enhancer Factor 2
The mechanisms underlying dopamine neuron loss in Parkinson's disease (PD) are not clearly defined. Here, we delineate a pathway… Expand
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Highly Cited
2005
Highly Cited
2005
Association with Class IIa Histone Deacetylases Upregulates the Sumoylation of MEF2 Transcription Factors
ABSTRACT The myocyte enhancer factor-2 (MEF2) family of transcription factors plays an important role in regulating cellular… Expand
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Highly Cited
2002
Highly Cited
2002
Regulation of GLUT4 biogenesis in muscle: evidence for involvement of AMPK and Ca(2+).
There is evidence suggesting that adaptive increases in GLUT4 and mitochondria in skeletal muscle occur in parallel. It has been… Expand
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Highly Cited
1994
Highly Cited
1994
Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis.
Members of the MEF2 family of transcription factors bind a conserved A/T-rich sequence in the control regions of many skeletal… Expand
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