FAQ

MED8 gene

Known as: MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 8, S. CEREVISIAE, HOMOLOG OF, MGC17544, ARC32 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
01220022018

Papers overview

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2018
2018
The Arabidopsis thaliana Mediator subunit MED8 regulates plant immunity to Botrytis Cinerea through interacting with the basic helix-loop-helix (bHLH) transcription factor FAMA.
The Mediator complex is at the core of transcriptional regulation and plays a central role in plant immunity. The MEDIATOR25… (More)
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2016
2016
Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types
The Mediator complex is a key regulator of gene transcription and several studies demonstrated altered expressions of particular… (More)
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Review
2013
Review
2013
The function of the Mediator complex in plant immunity
Upon pathogen infection, plants undergo dramatic transcriptome reprogramming to shift from normal growth and development to… (More)
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2012
2012
The Mediator complex subunit 8 regulates organ size in Arabidopsis thaliana.
Control of final organ size is a fundamental and core process of development of all multicellular organisms, but the mechanisms… (More)
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2010
2010
MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis.
The Mediator subunit MED1/TRAP220/DRIP205/PBP interacts directly with many nuclear receptors and was long thought to be… (More)
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2006
2006
Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response.
The NSs protein of Bunyamwera virus (Bunyaviridae) is an antiapoptotic interferon antagonist involved in silencing host protein… (More)
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2002
2002
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
The heterodimeric Elongin BC complex has been shown to interact in vitro and in cells with a conserved BC-box motif found in an… (More)
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2002
2002
Mediator factor Med8p interacts with the hexokinase 2: implication in the glucose signalling pathway of Saccharomyces cerevisiae.
In the presence of glucose the protein hexokinase 2 (Hxk2p), normally resident in the cytosol, is translocated to the nucleus… (More)
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