MCOLN3 gene

Known as: MCOLN3, TRP-ML3, TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, MUCOLIPIN SUBFAMILY, MEMBER 3 
 

Topic mentions per year

Topic mentions per year

2002-2017
0246820022017

Papers overview

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2010
2010
We conducted a high-throughput screen for small molecule activators of the TRPML3 ion channel, which, when mutated, causes… (More)
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2009
2009
TRPML3 is an inward rectifying Ca(2+) channel that is regulated by extracytosolic H(+). Although gain-of-function mutation in… (More)
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2008
2008
Varitint-waddler (Va and Va(J)) mice are deaf and have vestibular impairment, with inner ear defects that include the… (More)
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2008
2008
TRPML3 belongs to the TRPML subfamily of the transient receptor potential (TRP) channels. The A419P mutation in TRPML3 causes the… (More)
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Highly Cited
2007
Highly Cited
2007
Transient receptor potential (TRP) genes of the mucolipin subfamily (TRPML1-3 and MCOLN1-3) are presumed to encode ion channel… (More)
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2007
2007
Homozygote varitint-waddler (Va) mice, expressing a mutant isoform (A419P) of TRPML3 (mucolipin 3), are profoundly deaf and… (More)
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2007
2007
TRPML3 is a member of the TRPML subfamily of the transient receptor potential cation channel superfamily. The TRPML3(A419P… (More)
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2007
2007
In mammals, the mucolipin family includes three members mucolipin-1, mucolipin-2, and mucolipin-3 (MCOLN1-3). While mutations in… (More)
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Highly Cited
2006
Highly Cited
2006
Mucolipidosis type IV is an autosomal recessive lysosomal storage disorder characterized by severe neurodegeneration… (More)
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Highly Cited
2002
Highly Cited
2002
Deafness in spontaneously occurring mouse mutants is often associated with defects in cochlea sensory hair cells, opening an… (More)
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