Skip to search formSkip to main contentSkip to account menu

MCOLN2 gene

Known as: MCOLN2, TRP-ML2, MUCOLIPIN 2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children under the age of 15. In addition to genetic… 
2015
2015
Role of the transient receptor potential (TRP) channel gene expressions and TRP melastatin (TRPM) channel gene polymorphisms in obesity-related metabolic syndrome.
OBJECTIVE Metabolic syndrome (MetS) is correlated with increased cardiovascular risk and characterized by several factors… 
Review
2015
Review
2015
The mucolipin-2 (TRPML2) ion channel: a tissue-specific protein crucial to normal cell function
The discovery of the TRPML subfamily of ion channels has created an exciting niche in the fields of membrane trafficking, signal… 
2010
2010
Mucolipins : Intracellular TRPML 1-3 channels
0014-5793/$36.0 
2010
2010
Mucolipidosis type IV and the mucolipins.
MLIV (mucolipidosis type IV) is a neurodegenerative lysosomal storage disorder caused by mutations in MCOLN1, a gene that encodes… 
2009
2009
Constitutive Activity of the Human TRPML2 Channel Induces Cell Degeneration*
The mucolipin (TRPML) ion channel proteins represent a distinct subfamily of channel proteins within the transient receptor… 
Highly Cited
2007
Highly Cited
2007
A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse
Homozygote varitint-waddler (Va) mice, expressing a mutant isoform (A419P) of TRPML3 (mucolipin 3), are profoundly deaf and… 
Highly Cited
2007
Highly Cited
2007
Mucolipin‐2 Localizes to the Arf6‐Associated Pathway and Regulates Recycling of GPI‐APs
In mammals, the mucolipin family includes three members mucolipin‐1, mucolipin‐2, and mucolipin‐3 (MCOLN1–3). While mutations in… 
Highly Cited
2006
Highly Cited
2006
Lysosomal Localization of TRPML3 Depends on TRPML2 and the Mucolipidosis-associated Protein TRPML1*
Mucolipidosis type IV is an autosomal recessive lysosomal storage disorder characterized by severe neurodegeneration… 
2006
2006
TRPML cation channels regulate the specialized lysosomal compartment of vertebrate B-lymphocytes.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)