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MBTPS1 gene

Known as: MEMBRANE-BOUND TRANSCRIPTION FACTOR PROTEASE, SITE 1, SITE-1 PROTEASE, PCSK8 
National Institutes of Health

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2 relations
MBTPS2 genesite-1 protease

Papers overview

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2020
2020
Production of BBF2H7‐derived small peptide fragments via endoplasmic reticulum stress‐dependent regulated intramembrane proteolysis
Intramembrane cleavage of transmembrane proteins is a fundamental cellular process to produce important signals that elicit… 
Review
2016
Review
2016
[Proprotein convertases - family of serine proteases with a broad spectrum of physiological functions].
A large group of secretory proteins involved in proper functioning of living organisms, is synthesized as inactive precursor… 
2015
2015
Enediynyl peptides and iso-coumarinyl methyl sulfones as inhibitors of proprotein convertases PCSK8/SKI-1/S1P and PCSK4/PC4: Design, synthesis and biological evaluations.
2015
2015
Crosstalk between Bone and Muscle: Deletion of Mbtps1 in Bone Leads to Age‐Dependent Increase in Muscle Size and Contractile Function
Proprotein convertase Mbtps1 is required for transcription of bone matrix proteins including fibronectin, collagen XI, and PHEX… 
2015
2015
The membrane protein PrsS mimics σS in protecting Staphylococcus aureus against cell wall-targeting antibiotics and DNA-damaging agents.
Staphylococcus aureus possesses a lone extracytoplasmic function (ECF) sigma factor, σ(S). In Bacillus subtilis, the ECF sigma… 
2013
2013
Differential Recognition of Old World and New World Arenavirus Envelope Glycoproteins by Subtilisin Kexin Isozyme 1 (SKI-1)/Site 1 Protease (S1P)
ABSTRACT The arenaviruses are an important family of emerging viruses that includes several causative agents of severe… 
2012
2012
Hypopigmentation and Maternal-Zygotic Embryonic Lethality Caused by a Hypomorphic Mbtps1 Mutation in Mice
The site 1 protease, encoded by Mbtps1, mediates the initial cleavage of site 2 protease substrates, including sterol regulatory… 
2011
2011
Novel circular, cyclic and acyclic Ψ(CH(2)O) containing peptide inhibitors of SKI-1/S1P: synthesis, kinetic and biochemical evaluations.
BACKGROUND Subtilisin Kexin Isozyme-1 (SKI-1)/Site1Protease (S1P) is a Ca(+2)-dependent membrane bound pyrolysin-type serine… 
2008
2008
Potential Role of Proprotein Convertase SKI-1 in the Mineralization of Primary Bone
The biochemical mechanism controlling nucleation of mineral crystals in developing bone, along with the growth and propagation of… 
2004
2004
Prosomatostatin is proteolytically processed at the amino terminal segment by subtilase SKI-1
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