MAT2A gene

Known as: MAT2A, SAMS2, METHIONINE ADENOSYLTRANSFERASE II, ALPHA 
 
National Institutes of Health

Related topics

Related topics

2 relations
MAT1A geneMAT2B gene

Papers overview

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2016
2016
MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis.
Homozygous deletions of p16/CDKN2A are prevalent in cancer, and these mutations commonly involve co-deletion of adjacent genes… (More)
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2015
2015
MAT2A mutations predispose individuals to thoracic aortic aneurysms.
Up to 20% of individuals who have thoracic aortic aneurysms or acute aortic dissections but who do not have syndromic features… (More)
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2015
2015
Intersecting transcription networks constrain gene regulatory evolution
Epistasis—the non-additive interactions between different genetic loci—constrains evolutionary pathways, blocking some and… (More)
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2015
2015
PARTICLE, a Triplex-Forming Long ncRNA, Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation.
Exposure to low-dose irradiation causes transiently elevated expression of the long ncRNA PARTICLE (gene PARTICLE, promoter of… (More)
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2008
2008
Inhibition of hepatocelluar carcinoma MAT2A and MAT2beta gene expressions by single and dual small interfering RNA
RNA interference (RNAi) has been successfully applied in suppression of hepatic cancer genes. In hepatocelluar carcinoma cell… (More)
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Review
2005
Review
2005
Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer.
Two genes (MAT1A and MAT2A) encode for the essential enzyme methionine adenosyltransferase (MAT), which catalyzes the… (More)
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2000
2000
S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the differentiated status of the liver.
Methionine metabolism starts with the formation of S-adenosylmethionine (AdoMet), the most important biological methyl donor… (More)
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Highly Cited
1998
Highly Cited
1998
Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells.
Methionine adenosyltransferase (MAT) catalyzes the formation of S-adenosylmethionine (SAM), the principal methyl donor, and is… (More)
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1997
1997
Three differentially expressed S-adenosylmethionine synthetases from Catharanthus roseus: molecular and functional characterization
We describe the molecular and functional characterization of three closely related S-adenosyl-L-methionine synthetase (SAMS… (More)
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1978
1978
S-adenosyl methionine requiring mutants in Saccharomyces cerevisiae: Evidences for the existence of two methionine adenosyl transferases
Mutants requiring S-adenosyl methionine (SAM) for growth have been selected in Saccharomyces cerevisiae. Two classes of mutants… (More)
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