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MARK1 gene

Known as: KIAA1477, MARK1, PAR-1C 
National Institutes of Health

Papers overview

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2020
2020
MiR-486-5p Act as a Biomarker in Endometrial Carcinoma: Promotes Cell Proliferation, Migration, Invasion by Targeting MARK1
Background miRNA expression acts as a potential biomarker in many diseases including endometrial carcinoma (EC). miR-486-5p… 
2019
2019
Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms
ABSTRACT The MARK/PAR-1 family of kinases are conserved regulators of cell polarity that share a conserved C-terminal kinase… 
2018
2018
Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain.
2017
2017
Modulation of apical constriction by Wnt signaling is required for lung epithelial shape transition
In lung development, the apically constricted columnar epithelium forms numerous buds during the pseudoglandular stage… 
2017
2017
MARK1 is a Novel Target for miR-125a-5p: Implications for Cell Migration in Cervical Tumor Cells.
BACKGROUND Aberrant miRNA expression is associated with the development of several diseases including cervical cancer… 
2017
2017
Human TTBK1, TTBK2 and MARK1 kinase toxicity in Drosophila melanogaster is exacerbated by co-expression of human Tau
ABSTRACT Tau protein is involved in numerous human neurodegenerative diseases, and Tau hyper-phosphorylation has been linked to… 
2013
2013
The novel PAR-1-binding protein MTCL1 has crucial roles in organizing microtubules in polarizing epithelial cells
Summary The establishment of epithelial polarity is tightly linked to the dramatic reorganization of microtubules (MTs) from a… 
2013
2013
Identification of genes specifically methylated in Epstein–Barr virus‐associated gastric carcinomas
We studied the comprehensive DNA methylation status in the naturally derived gastric adenocarcinoma cell line SNU‐719, which was… 
Highly Cited
2006
Highly Cited
2006
Chemical genomic screening for methylation‐silenced genes in gastric cancer cell lines using 5‐aza‐2′‐deoxycytidine treatment and oligonucleotide microarray
To identify novel methylation‐silenced genes in gastric cancers, we carried out a chemical genomic screening, a genome‐wide… 
1995
1995
A simplified procedure for the subtractive cDNA cloning of photoassimilate-responding genes: isolation of cDNAs encoding a new class of pathogenesis-related proteins
Transgenic tobacco plants (ppa-1) constitutively expressing Escherichia coli pyrophosphatase behind the 35S CaMV promoter… 
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