FAQ

MAPK10 wt Allele

Known as: JNK3A, PRKM10, FLJ12099 
Human MAPK10 wild-type allele is located within 4q22.1-q23 and is approximately 344 kb in length. This allele, which encodes mitogen-activated… (More)

Topic mentions per year

Topic mentions per year

1995-2017
05101519952017

Related topics

Related topics

17 relations
4q22.1-q23Adipocytokine Signaling PathwayCell Cycle ControlCell Proliferation
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Broader (1)

MAPK10 gene

Related mentions per year

Related mentions per year

1944-2018
19401960198020002020
MAPK10 wt Allele
Signal Transduction
Cell Proliferation
Cell Cycle Control
Transcriptional Regulation
Phosphorylation

Papers overview

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Highly Cited
2012
Highly Cited
2012
JNK3 Perpetuates Metabolic Stress Induced by Aβ Peptides
Although Aβ peptides are causative agents in Alzheimer's disease (AD), the underlying mechanisms are still elusive. We report… (More)
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Highly Cited
2009
Highly Cited
2009
Pathogenic Huntingtin Inhibits Fast Axonal Transport by Activating JNK3 and Phosphorylating Kinesin
Selected vulnerability of neurons in Huntington's disease suggests that alterations occur in a cellular process that is… (More)
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2006
2006
Epigenetic disruption of two proapoptotic genes MAPK10/JNK3 and PTPN13/FAP-1 in multiple lymphomas and carcinomas through hypermethylation of a common bidirectional promoter
The Jun N-terminal kinase (JNK) subgroup of the mitogenactivated protein kinase (MAPK) superfamily is implicated in multiple… (More)
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2006
2006
Visual and both non-visual arrestins in their "inactive" conformation bind JNK3 and Mdm2 and relocalize them from the nucleus to the cytoplasm.
Arrestins bind active phosphorylated G protein-coupled receptors, terminating G protein activation. Receptor-bound non-visual… (More)
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Highly Cited
2005
Highly Cited
2005
Specific pathophysiological functions of JNK isoforms in the brain.
We have investigated the effect of JNK1 ko, JNK2 ko, JNK3 ko, JNK2+3 ko and c-JunAA mutation on neuronal survival in adult… (More)
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2004
2004
Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK).
Microtubule-associated protein tau in a hyperphosphorylated state is the major component of the filamentous lesions that define a… (More)
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Highly Cited
2003
Highly Cited
2003
A critical role of neural-specific JNK3 for ischemic apoptosis.
c-Jun N-terminal kinase (JNK) signaling is an important contributor to stress-induced apoptosis, but it is unclear whether JNK… (More)
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Highly Cited
2002
Highly Cited
2002
Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2.
beta-arrestins (betaarrs) are two highly homologous proteins that uncouple G protein-coupled receptors from their cognate G… (More)
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Highly Cited
2000
Highly Cited
2000
Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase.
c-Jun N-terminal protein kinase (JNK) and p38 mitogen-activated protein kinase are activated by stress and are implicated in… (More)
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1995
1995
p493F12 kinase: A novel MAP kinase expressed in a subset of neurons in the human nervous system
Monoclonal antibody 3F12 identifies a cytoplasmic antigen of 49 kDa in human hippocampus and neocortex. The distribution of 3F12… (More)
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