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MAPK10 wt Allele

Known as: JNK3A, PRKM10, FLJ12099 
Human MAPK10 wild-type allele is located within 4q22.1-q23 and is approximately 344 kb in length. This allele, which encodes mitogen-activated… Expand
National Institutes of Health

Related topics

Related topics

19 relations
4q22.1-q23Adipocytokine Signaling PathwayCell Cycle ControlCell Proliferation
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Broader (1)

MAPK10 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Pathogenic Huntingtin Inhibits Fast Axonal Transport by Activating JNK3 and Phosphorylating Kinesin
Selected vulnerability of neurons in Huntington's disease suggests that alterations occur in a cellular process that is… Expand
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Highly Cited
2007
Highly Cited
2007
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival
The innate immune system relies on evolutionally conserved Toll-like receptors (TLRs) to recognize diverse microbial molecular… Expand
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Highly Cited
2005
Highly Cited
2005
Specific pathophysiological functions of JNK isoforms in the brain
We have investigated the effect of JNK1 ko, JNK2 ko, JNK3 ko, JNK2+3 ko and c‐JunAA mutation on neuronal survival in adult… Expand
Highly Cited
2005
Highly Cited
2005
c‐Jun N‐terminal kinases (JNKs) mediate pro‐inflammatory actions of microglia
The activation and function of c‐Jun N‐terminal kinases (JNKs) were investigated in primary microglia cultures from neonatal rat… Expand
Highly Cited
2003
Highly Cited
2003
A critical role of neural-specific JNK3 for ischemic apoptosis
c-Jun N-terminal kinase (JNK) signaling is an important contributor to stress-induced apoptosis, but it is unclear whether JNK… Expand
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Highly Cited
2001
Highly Cited
2001
Arsenic induces apoptosis in rat cerebellar neurons via activation of JNK3 and p38 MAP kinases.
Primary cultures of rat cerebellar neurons were used to study mechanisms of arsenic neurotoxicity. Exposure to 5, 10, or 15… Expand
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Highly Cited
2000
Highly Cited
2000
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.
beta-Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein-coupled receptor (GPCR… Expand
Highly Cited
2000
Highly Cited
2000
Arsenite-Induced Apoptosis in Cortical Neurons Is Mediated by c-Jun N-Terminal Protein Kinase 3 and p38 Mitogen-Activated Protein Kinase
c-Jun N-terminal protein kinase (JNK) and p38 mitogen-activated protein kinase are activated by stress and are implicated in… Expand
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Highly Cited
1998
Highly Cited
1998
Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.
BACKGROUND The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein (MAP) kinase family, and regulate… Expand
Highly Cited
1995
Highly Cited
1995
p493F12 kinase: A novel MAP kinase expressed in a subset of neurons in the human nervous system
Monoclonal antibody 3F12 identifies a cytoplasmic antigen of 49 kDa in human hippocampus and neocortex. The distribution of 3F12… Expand
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