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MAPK10 wt Allele
Known as:
JNK3A
, PRKM10
, FLJ12099
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Human MAPK10 wild-type allele is located within 4q22.1-q23 and is approximately 344 kb in length. This allele, which encodes mitogen-activated…
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National Institutes of Health
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Related topics
Related topics
19 relations
4q22.1-q23
Adipocytokine Signaling Pathway
Cell Cycle Control
Cell Proliferation
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Broader (1)
MAPK10 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Pathogenic Huntingtin Inhibits Fast Axonal Transport by Activating JNK3 and Phosphorylating Kinesin
G. Morfini
,
Yi-Mei You
,
+11 authors
S. Brady
Nature Neuroscience
2009
Corpus ID: 6965311
Selected vulnerability of neurons in Huntington's disease suggests that alterations occur in a cellular process that is…
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Highly Cited
2007
Highly Cited
2007
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival
Y. Kim
,
P. Zhou
,
+6 authors
A. Ding
The Journal of experimental medicine
2007
Corpus ID: 10968353
The innate immune system relies on evolutionally conserved Toll-like receptors (TLRs) to recognize diverse microbial molecular…
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Highly Cited
2005
Highly Cited
2005
Specific pathophysiological functions of JNK isoforms in the brain
S. Brecht
,
R. Kirchhof
,
+15 authors
T. Herdegen
The European journal of neuroscience
2005
Corpus ID: 23572131
We have investigated the effect of JNK1 ko, JNK2 ko, JNK3 ko, JNK2+3 ko and c‐JunAA mutation on neuronal survival in adult…
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Highly Cited
2005
Highly Cited
2005
c‐Jun N‐terminal kinases (JNKs) mediate pro‐inflammatory actions of microglia
V. Waetzig
,
K. Czeloth
,
+7 authors
U. Hanisch
Glia
2005
Corpus ID: 40328245
The activation and function of c‐Jun N‐terminal kinases (JNKs) were investigated in primary microglia cultures from neonatal rat…
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Highly Cited
2003
Highly Cited
2003
A critical role of neural-specific JNK3 for ischemic apoptosis
C. Kuan
,
A. Whitmarsh
,
+9 authors
P. Rakic
Proceedings of the National Academy of Sciences…
2003
Corpus ID: 20511950
c-Jun N-terminal kinase (JNK) signaling is an important contributor to stress-induced apoptosis, but it is unclear whether JNK…
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Highly Cited
2001
Highly Cited
2001
Arsenic induces apoptosis in rat cerebellar neurons via activation of JNK3 and p38 MAP kinases.
U. Namgung
,
Z. Xia
Toxicology and applied pharmacology
2001
Corpus ID: 23330734
Primary cultures of rat cerebellar neurons were used to study mechanisms of arsenic neurotoxicity. Exposure to 5, 10, or 15…
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Highly Cited
2000
Highly Cited
2000
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.
P. McDonald
,
C. W. Chow
,
+5 authors
R. Lefkowitz
Science
2000
Corpus ID: 38778824
beta-Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein-coupled receptor (GPCR…
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Highly Cited
2000
Highly Cited
2000
Arsenite-Induced Apoptosis in Cortical Neurons Is Mediated by c-Jun N-Terminal Protein Kinase 3 and p38 Mitogen-Activated Protein Kinase
U. Namgung
,
Z. Xia
The Journal of Neuroscience
2000
Corpus ID: 7003185
c-Jun N-terminal protein kinase (JNK) and p38 mitogen-activated protein kinase are activated by stress and are implicated in…
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Highly Cited
1998
Highly Cited
1998
Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.
X. Xie
,
Y. Gu
,
+6 authors
M. Su
Structure
1998
Corpus ID: 25783135
BACKGROUND The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein (MAP) kinase family, and regulate…
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Highly Cited
1995
Highly Cited
1995
p493F12 kinase: A novel MAP kinase expressed in a subset of neurons in the human nervous system
A. A. Mohit
,
J. H. Martin
,
C. Miller
Neuron
1995
Corpus ID: 14107133
Monoclonal antibody 3F12 identifies a cytoplasmic antigen of 49 kDa in human hippocampus and neocortex. The distribution of 3F12…
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