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MAP3K11 gene

Known as: MAP3K11, MEKK11, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11 
National Institutes of Health

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Related topics

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mitogen-activated protein kinase kinase kinase 11

Papers overview

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2018
2018
Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3
Mixed-lineage kinase 3 (MLK3; also known as MAP3K11) is a Ser/Thr protein kinase widely expressed in normal and cancerous tissues… 
2018
2018
Abstract 2390: When MLK3 meets PAK1: Its implication in breast cancer tumorigenesis
2015
2015
Expression Data Analysis to Identify Biomarkers Associated with Asthma in Children
Asthma is characterized by recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing. It is usually… 
Review
2014
Review
2014
MLK3 as a regulator of disease progression in NASH
This article has been accepted for publication and undergone full peer review but has not been through the copyediting… 
2012
2012
HEK293T cells weremaintained in DMEMhigh glucosewith glutamine andHEK293GP2 cells weremaintained in DMEMhigh glucose with glutamine and sodium pyruvate. cDNA Constructs and Retrovirus Production…
Materials/Antibodies JNK1 (554286) and JNK1/2 (554285) antibodies were from PharMingen. Phospho-JNK1/2 (9251), Phospho-Src-Tyr… 
2011
2011
Cloning and Initial Functional Characterization of Mlk4α and Mlk4β
We have cloned a novel human mixed-lineage kinase gene, MLK4. Two alternatively spliced forms, MLK4α (580 aa) and MLK4β (1036 aa… 
2010
2010
Mixed Lineage Kinase-3 Stabilizes and Functionally Cooperates with TRIBBLES-3 to Compromise Mitochondrial Integrity in Cytokine-induced Death of Pancreatic Beta Cells*
Mixed lineage kinases (MLKs) have been implicated in cytokine signaling as well as in cell death pathways. Our studies show that… 
2009
2009
Role of mixed lineage kinase 3 in response of head and neck squamous cancer cell lines to epidermal growth factor receptor (EGFR) inhibition.
6076 Background: More efficacious treatments of head and neck squamous cancers (HNSCC) are urgently needed. HNSCC overexpress… 
1997
1997
A 3-Mb contig from D11S987 to MLK3, a gene-rich region in 11q13.
We have combined genetic, radiation-reduced somatic cell hybrid (RRH), fluorescent in situ hybridization (FISH), and physical… 
1997
1997
The mouse homologs of RELA and MLK3 are located within a 120-kb fragment on Chromosome 19
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