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MAP2K5 gene

Known as: MAP2K5, MEK5, MAPKK5 
National Institutes of Health

Papers overview

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2017
2017
Aberrant expression of MEK 5 in human hepatocellular carcinoma and its clinical significance
Mitogen/extracellular signal-regulated kinase kinase-5 [MEK5] has been confirmed to play a significant role in tumor… 
2016
2016
Targeting MEK5 Enhances Radiosensitivity of Human Prostate Cancer and Impairs Tumor-Associated Angiogenesis
2014
2014
Design, synthesis and evaluation of diphenylamines as MEK5 inhibitors
2011
2011
Molecular Pathways Targeting the BMK 1 MAP Kinase Pathway in Cancer Therapy
The big mitogen activated protein kinase 1 (BMK1) pathway is the most recently discovered and leaststudiedmammalianmitogen… 
2010
2010
Validation of the MEK5 and ERK5 pathway as targets for therapy in prostate cancer and analysis of the ERK5 signalling complex
Extracellular signal-regulated protein kinase 5 (ERK5) is a member of the mitogen activated protein (MAP) kinase family which is… 
2009
2009
ERK 5 Expression in Human Prostate Cancer Clinical Significance of Abnormal Extracellular Signal – Regulated Kinase 5 ( ERK 5 ) Expression in Human Prostate Cancer
The MEK5/ERK5 pathway has recently been implicated in prostate and breast carcinogenesis. Over-expression of MEK5 is associat ed… 
2007
2007
Abstract 1056: Association of ERK5 with MEK5 (upstream kinase of ERK5), but not ERK5 Kinase Activation, Inhibits Small Ubiquitin-related Modification of ERK5 Kinase (ERK5-SUMOylation), and Prevents…
2002
2002
Over-expression of MAP kinase kinase-5 (MEK5) in prostate cancer is related to presence of metastases and poor survival.
2001
2001
Expression of MAP kinase kinase-5 (MEK5) in human prostate cancer
1997
1997
Differential Expression of MEKI and MEK2 during Mouse Development1
Map/Erk kinase I (MEKI) and MEK2 activate the Erk/ MAP kinases and have been implicated in cell growth and differentiation. To…