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MAL2 gene

Known as: MAL proteolipid protein 2, MAL2, mal, T-cell differentiation protein 2 (gene/pseudogene) 
 
National Institutes of Health

Papers overview

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2018
2018
MiR-129 regulates growth and invasion by targeting MAL2 in papillary thyroid carcinoma.
MAL2, a member of the MAL proteolipid family, is essential for raft-mediated transport. In this study, we investigated the roles… Expand
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2017
2017
The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) are highly expressed in colorectal cancer and correlated with poor prognosis
The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) have been shown to be involved in tumorigenesis of various… Expand
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2014
2014
Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach.
Oxyntic atrophy in the stomach leads to chief cell transdifferentiation into spasmolytic polypeptide expressing metaplasia (SPEM… Expand
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2010
2010
The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2.
Transcytosis is a widespread pathway for apical targeting in epithelial cells. MAL2, an essential protein of the machinery for… Expand
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2010
2010
MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome
BackgroundThe four-transmembrane MAL2 protein is frequently overexpressed in breast carcinoma, and MAL2 overexpression is… Expand
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2008
2008
Mucin 1 (MUC1) is a novel partner for MAL2 in breast carcinoma cells
BackgroundThe MAL2 gene, encoding a four-transmembrane protein of the MAL family, is amplified and overexpressed in breast and… Expand
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2006
2006
Dynamics of MAL2 during glycosylphosphatidylinositol-anchored protein transcytotic transport to the apical surface of hepatoma HepG2 cells.
Delivery of glycosylphosphatidylinositol (GPI)-anchored proteins to the apical surface takes place by transcytosis in hepatocytes… Expand
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2004
2004
Expression and distribution of MAL2, an essential element of the machinery for basolateral-to-apical transcytosis, in human thyroid epithelial cells.
Polarized transport of newly synthesized proteins to the apical surface of epithelial cells takes place by a direct pathway from… Expand
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Highly Cited
2002
Highly Cited
2002
MAL2, a novel raft protein of the MAL family, is an essential component of the machinery for transcytosis in hepatoma HepG2 cells
Transcytosis is used alone (e.g., hepatoma HepG2 cells) or in combination with a direct pathway from the Golgi (e.g., epithelial… Expand
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2001
2001
Identification of MAL2, a novel member of the mal proteolipid family, though interactions with TPD52-like proteins in the yeast two-hybrid system.
The TPD52 (tumor protein D52)-like proteins are small coiled-coil motif-bearing proteins which were first identified though their… Expand
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