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MAGEA2 gene

Known as: MAGE2, MAGE family member A2, CT1.2 
This gene plays a role in p53-mediated signaling.
National Institutes of Health

Related topics

Related topics

6 relations
BAGE geneImmune responseMAGEA1 geneMAGEA2B gene
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Papers overview

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2012
2012
MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
MAGE-A genes are a subfamily of the melanoma antigen genes (MAGEs), whose expression is restricted to tumor cells of different… Expand
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2011
2011
BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer.
PURPOSE Aim of this study was to determine whether BORIS (Brother of the Regulator of Imprinted Sites) is a regulator of MAGEA2… Expand
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2009
2009
Induction of multiepitopic and long-lasting immune responses against tumour antigens by immunization with peptides, DNA and recombinant adenoviruses expressing minigenes.
The development of immunization strategies to induce strong and multiepitopic T-cell responses against tumour antigens is needed… Expand
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Highly Cited
2007
Highly Cited
2007
Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients.
This study aims to analyze the expression of 14 cancer/testis (CT) antigens in multiple myeloma (MM) to identify possible… Expand
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Highly Cited
2006
Highly Cited
2006
MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents.
The MAGE gene family is characterized by a conserved domain (MAGE Homology Domain). A subset of highly homologous MAGE genes… Expand
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2004
2004
Sequence and expression pattern of the human MAGE2 gene
We reported previously identification of the human MAGE1 gene, which encodes an antigen recognized on human melanoma MZ2-MEL by… Expand
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2004
2004
Cytotoxic T cell induction against human malignant melanoma cells using HLA-A24-restricted melanoma peptide cocktail.
Many human leukocyte antigen (HLA)-class I (mainly A*0201)-restricted peptide-specific cytotoxic T cells (CTLs) have been derived… Expand
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Highly Cited
2003
Highly Cited
2003
Overexpression of MAGE/GAGE genes in paclitaxel/doxorubicin-resistant human cancer cell lines.
Previous studies directed at identifying paclitaxel resistance genes in a paclitaxel-resistant subclone of the human ovarian… Expand
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2002
2002
Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma.
Cancer-testis antigens expressed by different-histotype transformed cells are suitable targets for tumor immunotherapy. However… Expand
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Highly Cited
1998
Highly Cited
1998
The multi-epitope approach for immunotherapy for cancer: identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors.
One approach to development of specific cancer immunotherapy relies on the induction of cytotoxic T lymphocytes (CTL) specific… Expand
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