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MAGEA2 gene

Known as: MAGE2, MAGE family member A2, CT1.2 
This gene plays a role in p53-mediated signaling.
National Institutes of Health

Related topics

Related topics

6 relations
BAGE geneImmune responseMAGEA1 geneMAGEA2B gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
MAGE-A genes are a subfamily of the melanoma antigen genes (MAGEs), whose expression is restricted to tumor cells of different… 
2011
2011
The role of MAGEA2 in head and neck cancer.
OBJECTIVE To examine the role of MAGEA2 in the tumorigenesis of head and neck squamous cell carcinoma (HNSCC). DESIGN Primary… 
Highly Cited
2010
Highly Cited
2010
Expression of cancer/testis antigens in prostate cancer is associated with disease progression
The cancer/testis antigens (CTAs) are a unique group of proteins normally expressed in germ cells but aberrantly expressed in… 
Highly Cited
2008
Highly Cited
2008
Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients.
This study aims to analyze the expression of 14 cancer/testis (CT) antigens in multiple myeloma (MM) to identify possible… 
Highly Cited
2006
Highly Cited
2006
MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents.
The MAGE gene family is characterized by a conserved domain (MAGE Homology Domain). A subset of highly homologous MAGE genes… 
Highly Cited
2004
Highly Cited
2004
Sequence and expression pattern of the human MAGE2 gene
We reported previously identification of the human MAGE1 gene, which encodes an antigen recognized on human melanoma MZ2-MEL by… 
2004
2004
Cytotoxic T cell induction against human malignant melanoma cells using HLA-A24-restricted melanoma peptide cocktail.
Many human leukocyte antigen (HLA)-class I (mainly A*0201)-restricted peptide-specific cytotoxic T cells (CTLs) have been derived… 
Highly Cited
2003
Highly Cited
2003
Overexpression of MAGE/GAGE genes in paclitaxel/doxorubicin-resistant human cancer cell lines.
Previous studies directed at identifying paclitaxel resistance genes in a paclitaxel-resistant subclone of the human ovarian… 
Highly Cited
2002
Highly Cited
2002
Promoter Methylation Controls the Expression of MAGE2, 3 and 4 Genes in Human Cutaneous Melanoma
Cancer-testis antigens expressed by different-histotype transformed cells are suitable targets for tumor immunotherapy. However… 
Highly Cited
1998
Highly Cited
1998
The multi-epitope approach for immunotherapy for cancer: identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors.
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