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MAFA wt Allele

Known as: RIPE3b1, hMafA, v-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A Gene 
Human MAFA wild-type allele is located in the vicinity of 8q24.3 and is approximately 11 kb in length. This allele, which encodes transcription… Expand
National Institutes of Health

Papers overview

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2011
2011
Pancreatic β-cell-restricted expression of insulin is established through several critical cis-regulatory elements located in the… Expand
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2009
2009
Mammalian MafA/RIPE3b1 is an important glucose-responsive transcription factor that regulates function, maturation, and survival… Expand
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Highly Cited
2003
Highly Cited
2003
The C1/RIPE3b1 (-118/-107 bp) binding factor regulates pancreatic-beta-cell-specific and glucose-regulated transcription of the… Expand
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Highly Cited
2002
Highly Cited
2002
Of the three critical enhancer elements that mediate beta-cell-specific and glucose-responsive expression of the insulin gene… Expand
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2001
2001
Transcription factors binding the insulin enhancer region, RIPE3b, mediate beta-cell type-specific and glucose-responsive… Expand
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Highly Cited
1996
Highly Cited
1996
We have shown previously that chronic exposure of HIT-T15 cells to supraphysiologic glucose concentrations causes decreased… Expand
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Highly Cited
1995
Highly Cited
1995
The most important regulator of insulin gene expression in pancreatic beta- cells is glucose, which affects gene transcription… Expand
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1995
1995
The most important regulator of insulin expression in islet beta-cells is glucose, which stimulates insulin gene transcription… Expand
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1994
1994
The insulin gene is expressed exclusively in pancreatic islet beta cells. The principal regulator of insulin gene transcription… Expand
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