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MAFA wt Allele

Known as: RIPE3b1, hMafA, v-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A Gene 
Human MAFA wild-type allele is located in the vicinity of 8q24.3 and is approximately 11 kb in length. This allele, which encodes transcription… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Pancreatic β-cell-restricted expression of insulin is established through several critical cis-regulatory elements located in the… Expand
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2007
2007
Transcription factors, such as PDX-1, that normally mediate pancreatic development are capable of inducing hepatic progenitor… Expand
Highly Cited
2003
Highly Cited
2003
ABSTRACT The C1/RIPE3b1 (−118/−107 bp) binding factor regulates pancreatic-β-cell-specific and glucose-regulated transcription of… Expand
Highly Cited
2003
Highly Cited
2003
Pancreatic duodenal homeobox factor-1, PDX-1, is required for pancreas development, islet cell differentiation, and the… Expand
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Highly Cited
2002
Highly Cited
2002
Of the three critical enhancer elements that mediate β-cell-specific and glucose-responsive expression of the insulin gene, only… Expand
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2001
2001
Transcription factors binding the insulin enhancer region, RIPE3b, mediate β-cell type-specific and glucose-responsive expression… Expand
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Highly Cited
1996
Highly Cited
1996
We have shown previously that chronic exposure of HIT-T15 cells to supraphysiologic glucose concentrations causes decreased… Expand
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Highly Cited
1995
Highly Cited
1995
The most important regulator of insulin gene expression in pancreatic beta- cells is glucose, which affects gene transcription… Expand
Highly Cited
1995
Highly Cited
1995
The most important regulator of insulin expression in islet beta-cells is glucose, which stimulates insulin gene transcription… Expand
Highly Cited
1994
Highly Cited
1994
The insulin gene is expressed exclusively in pancreatic islet beta cells. The principal regulator of insulin gene transcription… Expand