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MACROD2 gene

Known as: MACRO DOMAIN-CONTAINING 2, MACRO domain containing 2, MACROD2 
National Institutes of Health

Papers overview

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Review
2020
Review
2020
The Controversial Roles of ADP-Ribosyl Hydrolases MACROD1, MACROD2 and TARG1 in Carcinogenesis
Post-translational modifications (PTM) of proteins are crucial for fine-tuning a cell’s response to both intracellular and… 
2020
2020
MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3β/β-catenin signaling
Structural variations (SVs) influence the development and progression of multiple types of cancer. The genes affected by SVs in… 
2018
2018
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors.
ADP-ribosylation is an important posttranslational protein modification that regulates diverse biological processes, controlled… 
2018
2018
Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2
MACRO Domain Containing 2 (MacroD2) is a neurodevelopmental disorder-related mono-ADP-ribosylhydrolase. Molecular features of… 
2018
2018
MACROD2 deletions cause impaired PARP1 activity and chromosome instability in colorectal cancer
The MACRO domain containing 2 ( MACROD2 ) locus on chromosome 20p12.1 is a frequent site of focal deletion in various human… 
2018
2018
Genome‐wide scan for circulating vascular adhesion protein‐1 levels: MACROD2 as a potential transcriptional regulator of adipogenesis
Vascular adhesion protein‐1 (VAP‐1) is a membrane‐bound amine oxidase highly expressed in mature adipocytes and released into the… 
2018
2018
Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults
ADP-ribosylation is an important post-translational protein modification that regulates diverse biological processes, controlled… 
2016
2016
ATM induces MacroD2 nuclear export upon DNA damage
ADP-ribosylation is a dynamic post-translation modification that regulates the early phase of various DNA repair pathways by… 
2015
2015
High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer
Background Cancer is caused by somatic DNA alterations such as gene point mutations, DNA copy number aberrations (CNA) and… 
2008
2008
Lack of C20orf133 and FLRT3 mutations in 43 patients with Kabuki syndrome in Japan
Kabuki syndrome (KS, OMIM 147920), also known as Niikawa–Kuroki syndrome, is a multiple congenital anomalies/mental retardation… 
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