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M2 Macrophage

A macrophage that produces high levels of interleukin (IL)-10, TGF-beta and low levels of IL-12 and converts arginine to ornithine. These cells may… 
National Institutes of Health

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Related topics

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Immune system

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Aggressive Crosstalk Between Fatty Acids and Inflammation in Macrophages and Their Influence on Metabolic Homeostasis
From the immunological point of view, macrophages are required to maintain metabolic homeostasis. Recently, there has been an… 
2017
2017
Role of M2 Macrophages in Sepsis-Induced Acute Kidney Injury.
BACKGROUND Sepsis is a major cause of acute kidney injury (AKI), with high rates of morbidity and mortality. M2 macrophages have… 
2017
2017
Multivalent polymers displaying M2 macrophage-targeting peptides improve target binding avidity and serum stability.
Tumor-associated macrophages (TAMs) display a spectrum of phenotypes ranging from pro-tumoral/anti-inflammatory "M2-like" to anti… 
2016
2016
miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBPα
Macrophages can acquire a variety of polarization status and functions: classically activated macrophages (M1 macrophages… 
2016
2016
Interleukin‐4‐Clicked Surfaces Drive M2 Macrophage Polarization
Driving macrophage (Mϕ) polarization into the M2 phenotype provides potential against inflammatory diseases. Interleukin‐4 (IL‐4… 
2015
2015
Comparative local immunogenic potential of scaffolds prepared from porcine cholecyst, jejunum, and urinary bladder in rat subcutaneous model.
Extracellular matrices isolated from several mammalian organs/tissues have found several clinical uses as xenografts or implants… 
2015
2015
Effect of rTsP53 on the M1/M2 activation of bone-marrow derived macrophage in vitro.
We investigated that if rTsP53 could be used to activate bone-marrow derived macrophage (BMDM) into M2 macrophage and stop M1… 
2013
2013
Overexpression of Semaphorin 4 D Indicates Poor Prognosis and Prompts Monocyte Differentiation toward M 2 Macrophages in Epithelial Ovarian Cancer
Epithelial ovarian cancer (EOC) is the leading killer among all gynecological malignancies (Siegel et al., 2012). Over 70% of EOC… 
2013
2013
Conditioned medium from alternatively activated macrophages induce mesangial cell apoptosis via the effect of Fas.
2010
2010
Low- but not high-dose FK506 treatment confers atheroprotection due to alternative macrophage activation and unaffected cholesterol levels
Summary Previous studies showed both proand anti-atherogenic effects of immunosuppressant drug FK506 on atherosclerosis. As these… 
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