M2 Macrophage

A macrophage that produces high levels of interleukin (IL)-10, TGF-beta and low levels of IL-12 and converts arginine to ornithine. These cells may… (More)
National Institutes of Health

Papers overview

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2016
2016
Metabolites from intestinal microbes modulate the mucosal immune system by regulating the polarization and expansion of T cells… (More)
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2016
2016
Alzheimer's disease (AD) is the most common neurodegenerative disorder in the elderly population. Neuroinflammation induced by… (More)
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Highly Cited
2015
Highly Cited
2015
Macrophages activated by the TLR4 agonist LPS undergo dramatic changes in their metabolic activity. We here show that LPS induces… (More)
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2014
2014
Increasing evidence suggests the heterogeneity of macrophage phenotype and function ultimately determines the outcome of diabetic… (More)
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2014
2014
Tumor-associated macrophages (TAMs) are M2-polarized macrophages that infiltrate the tumor microenvironment and promote… (More)
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2013
2013
Chronic arterial occlusion leads to growth of collaterals - a process termed arteriogenesis, in which macrophages play a… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE Recent studies suggest that exchange of macrophage phenotype (M1/M2) in adipose tissue is associated with chronic low… (More)
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Highly Cited
2009
Highly Cited
2009
Macrophages dominate sites of CNS injury in which they promote both injury and repair. These divergent effects may be caused by… (More)
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Highly Cited
2009
Highly Cited
2009
Macrophages function as control switches of the immune system, providing a balance between pro- and anti-inflammatory responses… (More)
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Highly Cited
2008
Highly Cited
2008
Monocytes are primary targets for human CMV (HCMV) infection and are proposed to be responsible for hematogenous dissemination of… (More)
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