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Lysyl Oxidase Homolog 2

Known as: Lysyl Oxidase-Like Protein 2, Lysyl Oxidase-Related Protein 2, Lysyl Oxidase-Related Protein WS9-14 
Lysyl oxidase homolog 2 (774 aa, ~87 kDa) is encoded by the human LOXL2 gene. This protein is involved in the regulation of crosslinking in collagens… Expand
National Institutes of Health

Related topics

Related topics

10 relations
AgingCell AdhesionEnzyme GeneExtracellular Protein
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia
Preeclampsia is a pregnancy-specific disorder that is a major cause of maternal and fetal morbidity and mortality with a… Expand
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2019
2019
Salidroside ameliorated hypoxia‐induced tumorigenesis of BxPC‐3 cells via downregulating hypoxia‐inducible factor (HIF)‐1α and LOXL2
Herein, we found that salidroside suppressed hypoxia‐inducible factor 1 alpha (HIF‐1α) and lysyl oxidase‐like protein 2 (LOXL2… Expand
2018
2018
Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer
Lysyl oxidase (LOX) family genes, particularly lysyl oxidase-like protein 2 (LOXL2), have been implicated in carcinogenesis… Expand
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2018
2018
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
BACKGROUND & AIMS The lysyl oxidase-like protein 2 (LOXL2) promotes stabilization of the extracellular matrix, chemotaxis, cell… Expand
Review
2016
Review
2016
New frontiers in fibrotic disease therapies: The focus of the Joan and Joel Rosenbloom Center for Fibrotic Diseases at Thomas Jefferson University.
Fibrotic diseases constitute a world-wide major health problem, but research support remains inadequate in comparison to the need… Expand
2014
2014
Insilico study of anti-carcinogenic lysyl oxidase-like 2 inhibitors
Lysyl oxidase homolog 2 (LOXL2), also known as lysyl oxidase-like protein 2 is recently been explored as regulator of… Expand
2010
2010
The role of LOX and LOXL2 in wound healing after glaucoma filtration surgery
Purpose Lysyl oxidase (LOX) and lysyl oxidase‐like protein 2 (LOXL2) are involved in the crosslinking of collagen and elastin. We… Expand
2009
2009
I016 Extracellular matrix remodelling in abdominal aortic aneurysm: involvement of LOXL2 and TG2 reticulation enzymes
Abdominal aortic aneurysms (AAA) are the third cause of cardiovascular mortality in industrialized countries. AAA consist in… Expand
2009
2009
The role of lox and LOXL2 in inflammation and fibrosis in a laser induced mouse model
Purpose Lysyl oxidase (LOX) and lysyl oxidase-like protein 2 (LOXL2) are involved in the cross-linking of collagen and elastin in… Expand
2009
2009
The effect of upregulated LOX and LOXL2 on inflammation and fibrosis in a laser induced CNV model
Purpose Lysyl oxidase (LOX) and lysyl oxidase-like protein 2 (LOXL2) are involved in the cross-linking of collagen and elastin in… Expand
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