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Low Molecular Weight Cyclin E

Known as: LMW-E 
Proteolytically processed forms of cyclin E proteins, which are specifically generated in tumors that overexpress cyclin E proteins.
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Cyclin E, a regulatory subunit of cyclin-dependent kinase 2 (CDK2), is central to the initiation of DNA replication at the G1/S… Expand
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2016
2016
Purpose: Low molecular weight cyclin E (LMW-E) detected by Western blot analysis predicts for reduced breast cancer survival… Expand
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2016
2016
Cyclin E is altered in nearly a third of invasive breast cancers where it is a powerful independent predictor of survival in… Expand
2016
2016
Cyclin E and its co-activator, phospho-cyclin-dependent kinase 2 (p-CDK2), regulate G1 to S phase transition and their… Expand
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2013
2013
Expression of cyclin E proteolytic cleavage products, low-molecular weight cyclin E (LMW-E), is associated with poor clinical… Expand
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2012
2012
Cyclin E, together with cyclin-dependent kinase 2 (CDK2), functions as a gatekeeper to promote G1/S transitions and the… Expand
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2011
2011
Low molecular weight cyclin E (LMW-E) plays an important oncogenic role in breast cancer. LMW-E, which is not found in normal… Expand
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Highly Cited
2010
Highly Cited
2010
Overexpression of the low molecular weight isoforms (LMW-E) of cyclin E induces chromosome instability; however, the degree to… Expand
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Highly Cited
2010
Highly Cited
2010
Purpose: Low-molecular-weight cyclin E (LMW-E) in breast cancer cells induces genomic instability and resistance to inhibition by… Expand
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2010
2010
The cyclin E-cyclin-dependent kinase 2 (CDK2) complex accelerates entry into the S phase of the cell cycle and promotes… Expand
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