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Low Molecular Weight Cyclin E

Known as: LMW-E 
Proteolytically processed forms of cyclin E proteins, which are specifically generated in tumors that overexpress cyclin E proteins.
National Institutes of Health

Papers overview

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2017
2017
  • 2017
  • Corpus ID: 52253422
As depicted in this figure, we have discovered that the LMW-E isoforms are potent oncogenes that act early in the etiology of… 
2016
2016
Deregulation of the cell cycle machinery is a hallmark of most cancers, making the positive regulators of cell cycle such as… 
2015
2015
Pro-inflammatory IL-17 cytokines were initially described for their pathogenic role in chronic inflammatory diseases and… 
2015
2015
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA Deregulation of the cell cycle machinery is a… 
2015
2015
Deregulation of the cell cycle machinery is a hallmark of breast cancer, facilitating aberrant proliferation that fuels… 
2015
2015
Purpose: While we know that many cytotoxic chemotherapeutic agents act to modulate the cell cycle, the role of cyclin E as a… 
2014
2014
163 Background: Low molecular weight cyclin E (LMW-E) isoforms are overexpressed in a majority (~70%) of triple-negative breast… 
2013
2013
Inflammatory breast cancer (IBC) is a rare, highly aggressive form of breast cancer, accounting for 2-5% of all breast cancers in… 
2012
2012
Cyclin E, together with cyclin-dependent kinase 2 (CDK2), functions as a gatekeeper to promote G1/S transitions and the… 
2011
2011
Background: Triple negative breast carcinomas (TNBCs) are aggressive malignancies that lack effective therapeutic targets but…