FAQ

Long Qt Syndrome 6

Known as: LQT6 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
0120032017

Related topics

Related topics

7 relations
Autosomal dominant inheritanceKCNE2 geneSudden Cardiac DeathSyncope
(More)

Broader (1)

Long QT Syndrome

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
Long Qt Syndrome 6
Autosomal dominant inheritance
Ventricular Fibrillation
Syncope
Sudden Cardiac Death
Torsades de Pointes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Loss-of-Function KCNE2 Variants: True Monogenic Culprits of Long-QT Syndrome or Proarrhythmic Variants Requiring Secondary Provocation?
BACKGROUND Insight into type 6 long-QT syndrome (LQT6), stemming from mutations in the KCNE2-encoded voltage-gated channel… (More)
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2014
2014
KCNE2 modulates cardiac L-type Ca(2+) channel.
KCNE2 plays an important role in maintaining cardiac electrical stability. Mutations in KCNE2 have been linked to long-QT… (More)
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2013
2013
Clinical utility gene card for: Long-QT Syndrome (types 1–13)
1.3 Name of the analysed genes or DNA/chromosome segments LQT1: KCNQ1, 11p15.5; LQT2: KCNH2, 7q35-q36; LQT3: SCN5A, 3p21; LQT4… (More)
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Review
2010
Review
2010
Contemporary Reviews in Cardiovascular Medicine Drug-Induced Arrhythmia
Prolongation of the QTc interval has been associated with proarrhythmia resulting from a potentially fatal form of polymorphic… (More)
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Highly Cited
2007
Highly Cited
2007
Postmortem long QT syndrome genetic testing for sudden unexplained death in the young.
OBJECTIVES This study sought to determine the spectrum and prevalence of long QT syndrome (LQTS)-associated mutations in a large… (More)
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Highly Cited
2005
Highly Cited
2005
Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing.
OBJECTIVES The purpose of this study was to determine the spectrum and prevalence of cardiac channel mutations among a large… (More)
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2004
2004
The common SCN5A mutation R1193Q causes LQTS-type electrophysiological alterations of the cardiac sodium channel.
L ong QT syndrome (LQTS) is a prototypic arrhythmic disorder that is characterised by prolonged QT interval (or QTc) on… (More)
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2004
2004
KCNE2 protein is expressed in ventricles of different species, and changes in its expression contribute to electrical remodeling in diseased hearts.
BACKGROUND Mutations in KCNE2 have been linked to long-QT syndrome (LQT6), yet KCNE2 protein expression in the ventricle and its… (More)
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Review
2003
Review
2003
[Value of genetic testing in the management of the congenital long QT syndrome].
The congenital long QT syndrome (LQTS) is a variable clinical and genetic entity characterised by prolongation of the QT interval… (More)
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